Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4549634 | 0.83 | FOLH1 (0.45) | CA1CA2CA9NPC1RAB9A | |
| SCHEMBL2622526 | 0.82 | BACE1 (0.43) | CA1CA2CA9FFAR4FFAR1 | |
| SCHEMBL2622531 | 0.80 | PTGS2 (0.42) | CA1CA2CA9POLBRECQL | |
| SCHEMBL16590818 | 0.78 | PTGS2 (0.41) | POLBRECQLSLC9A1PTGS2ALDH1A1 | |
| SCHEMBL13557157 | 0.76 | SRD5A2 (0.46) | ALDH1A1 | |
| SCHEMBL13557160 | 0.76 | SRD5A2 (0.45) | CA1CA2CA9 | |
| SCHEMBL13557159 | 0.75 | HTT (0.47) | POLBRECQLESR2ALDH1A1MAOA | |
| SCHEMBL19308001 | 0.74 | ALDH1A1 (0.57) | POLBRECQLSLC9A1PTGS2NPC1 | |
| SCHEMBL2622527 | 0.74 | MAOB (0.43) | FFAR4FFAR1ALDH1A1MAOAMAOB | |
| SCHEMBL13557158 | 0.74 | HTT (0.46) | POLBRECQLESR2ALDH1A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895118-B2 | Negative dispersion retardation plate and achromatic circular polarizer | CRYSOPTIX K.K. (JP) | 2014-11-25 | — | — | US | disclosed |
| US-20140334002-A1 | PATTERNED RETARDER | CRYSOPTIX KK (JP) | 2014-11-13 | — | — | US | disclosed |
| US-20120113380-A1 | NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER | CRYSOPTIX KK (JP) | 2012-05-10 | — | — | US | disclosed |