Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 4/20 | 0.41 |
| ▸ | RXRB | P28702 | 4/20 | 0.41 |
| ▸ | RXRG | P48443 | 3/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4549636 | 0.83 | CA1 (0.37) | CA1CA2CA9NPC1RAB9A | |
| SCHEMBL360967 | 0.81 | CDC25B (0.47) | FOLH1RXRARXRBRXRGSRD5A2 | |
| SCHEMBL13316464 | 0.76 | RARB (0.53) | RXRARXRBRXRGSRD5A2SMN1; SMN2 | |
| SCHEMBL13316462 | 0.74 | ALDH1A1 (0.56) | RXRARXRBRXRGSRD5A2CA12 | |
| SCHEMBL2622532 | 0.73 | SRD5A2 (0.39) | FOLH1RXRASRD5A2CA12CA1 | |
| SCHEMBL361052 | 0.73 | CSNK2A2 (0.50) | RXRARXRBSRD5A2CA12CA1 | |
| SCHEMBL360228 | 0.70 | CDC25B (0.53) | CA12CA1CA2CA9CA14 | |
| SCHEMBL361093 | 0.70 | ESR2 (0.36) | FOLH1TSHRHPGD | |
| SCHEMBL2622534 | 0.70 | CA1 (0.35) | FOLH1CA1CA2 | |
| SCHEMBL4549635 | 0.70 | POLB (0.35) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895118-B2 | Negative dispersion retardation plate and achromatic circular polarizer | CRYSOPTIX K.K. (JP) | 2014-11-25 | — | — | US | disclosed |
| US-20140334002-A1 | PATTERNED RETARDER | CRYSOPTIX KK (JP) | 2014-11-13 | — | — | US | disclosed |
| US-20120113380-A1 | NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER | CRYSOPTIX KK (JP) | 2012-05-10 | — | — | US | disclosed |