Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4550325 | 0.74 | — | — | |
| SCHEMBL21041002 | 0.69 | HTR2C (0.43) | L3MBTL1DRD2DRD3 | |
| SCHEMBL17159713 | 0.62 | L3MBTL1 (0.36) | L3MBTL1SMN1; SMN2LMNATSHR | |
| SCHEMBL18611234 | 0.62 | L3MBTL1 (0.39) | L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL23639333 | 0.62 | L3MBTL1 (0.41) | L3MBTL1KDM4ESMN1; SMN2KCNH2 | |
| SCHEMBL22595338 | 0.62 | L3MBTL1 (0.41) | L3MBTL1SMN1; SMN2LMNAKCNH2 | |
| SCHEMBL6607250 | 0.62 | MEN1 (0.51) | L3MBTL1SMN1; SMN2LMNATSHR | |
| SCHEMBL22595335 | 0.62 | L3MBTL1 (0.41) | L3MBTL1KDM4ESMN1; SMN2LMNATSHR | |
| SCHEMBL23414825 | 0.62 | L3MBTL1 (0.45) | L3MBTL1SMN1; SMN2 | |
| SCHEMBL3966140 | 0.61 | NUDT1 (0.43) | L3MBTL1KDM4ESMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012053186-A1 | ARYLAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2012-04-26 | — | — | WO | disclosed |