Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2806923 | 0.79 | ALDH1A1 (0.45) | ALDH1A1TSHRLMNANPC1SMN1; SMN2 | |
| SCHEMBL27714943 | 0.78 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNANPC1SMN1; SMN2 | |
| SCHEMBL4599422 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TSHRLMNANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5424757 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TSHRLMNANPC1SMN1; SMN2 | |
| SCHEMBL31352127 | 0.75 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNANPC1PTPN1 | |
| SCHEMBL31352358 | 0.75 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNANPC1PTPN1 | |
| SCHEMBL31352138 | 0.73 | LMNA (0.58) | ALDH1A1TSHRLMNANPC1PTPN1 | |
| SCHEMBL27533039 | 0.73 | ALDH1A1 (0.76) | ALDH1A1TSHRLMNANPC1SMN1; SMN2 | |
| SCHEMBL28036519 | 0.73 | MAPK14 (0.46) | ALDH1A1LMNANPC1MAPK14GABRP | |
| SCHEMBL7811465 | 0.72 | MAPK14 (0.43) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2033955-A1 | Urea derivatives of 1H-pyrazol-4-carboxylic acid with neutrophil chemotaxis inhibiting activity | Universita' Degli Studi Di Genova (IT) | 2009-03-11 | — | — | EP | disclosed |