Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Chloro-Benzoic Acid SCHEMBL28384 | 0.82 | TSHR (1.00) | TSHRALOX15SRD5A2ALDH1A1TP53 | |
| 4-Chloro-Benzoic Acid SCHEMBL1331727 | 0.82 | TSHR (1.00) | TSHRALOX15SRD5A2ALDH1A1TP53 | |
| SCHEMBL4030936 | 0.82 | TSHR (0.71) | TSHRALOX15SRD5A2ALDH1A1TP53 | |
| 4-Chloro-Benzoic Acid SCHEMBL9120766 | 0.80 | TSHR (0.94) | TSHRALOX15SRD5A2ALDH1A1TP53 | |
| 4-Chloro-Benzoic Acid SCHEMBL2918294 | 0.80 | TSHR (0.94) | TSHRALOX15SRD5A2ALDH1A1TP53 | |
| 4-Chloro-Benzoic Acid SCHEMBL7634885 | 0.80 | TSHR (0.94) | TSHRALOX15SRD5A2ALDH1A1TP53 | |
| 4-Chloro-Benzoic Acid SCHEMBL3150134 | 0.80 | TSHR (0.94) | TSHRALOX15SRD5A2ALDH1A1TP53 | |
| 4-Chloro-Benzoic Acid SCHEMBL8024007 | 0.80 | TSHR (0.94) | TSHRALOX15SRD5A2ALDH1A1TP53 | |
| 4-Chloro-Benzoic Acid SCHEMBL9493329 | 0.80 | TSHR (0.94) | TSHRALOX15SRD5A2ALDH1A1TP53 | |
| 4-Chloro-Benzoic Acid SCHEMBL32665742 | 0.80 | TSHR (0.94) | TSHRALOX15SRD5A2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180334430-A1 | ARYLSULFANYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) | 2018-11-22 | — | — | US | disclosed |
| US-20090258817-A1 | ARYLSULFANYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | NOVO NORDISK A/S (DK) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258817-A1 | ARYLSULFANYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | ABCB7, ABCB4, PAICS | TSHR 2449/4885ALOX15 1109/4885SRD5A2 2382/4885 |
| US-20180334430-A1 | ARYLSULFANYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | ABCB7, ABCB4, PAICS | TSHR 2449/4885ALOX15 1109/4885SRD5A2 2382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.