SCHEMBL4551078

SCHEMBL4551078

CCCCCOC(C(C)=O)C(O)CO

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.41
ALDH1A1 P00352 1/20 0.39
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39
CES2 O00748 1/20 0.39
PLA2G2C Q5R387 1/20 0.38
MGAM O43451 3/20 0.38
TSHR P16473 2/20 0.37
KDM4E B2RXH2 1/20 0.37
DUSP3 P51452 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6151119 0.98 USP2 (0.43) USP2CES2PLA2G2CMGAMTSHR
SCHEMBL29249582 0.98 USP2 (0.43) USP2CES2PLA2G2CMGAMTSHR
SCHEMBL6150703 0.98 USP2 (0.43) USP2CES2PLA2G2CMGAMTSHR
SCHEMBL6150210 0.89 CNR1 (0.52) ALDH1A1CNR1CNR2
SCHEMBL6150630 0.89 CNR1 (0.52) ALDH1A1CNR1CNR2
SCHEMBL8105632 0.83 USP2 (0.42) USP2ALDH1A1MGAMKDM4EDUSP3
SCHEMBL7455637 0.83 USP2 (0.42) USP2ALDH1A1MGAMKDM4EDUSP3
SCHEMBL27982048 0.81 CES2 (0.44) CES2KDM4EDUSP3MEN1KMT2A
SCHEMBL8345461 0.81 CES2 (0.44) CES2KDM4EDUSP3MEN1KMT2A
SCHEMBL4813181 0.81 USP2 (0.43) USP2ALDH1A1CNR1CNR2MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0287652-B1 SERUM-FREE MEDIUM FOR THE PROLIFERATION OF LYMPHOKINE-ACTIVATED KILLER CELLS LIFE TECHNOLOGIES INC (US) 1994-01-12 EP claimed
EP-0287652-A4 SERUM-FREE MEDIUM FOR THE PROLIFERATION OF LYMPHOKINE-ACTIVATED KILLER CELLS. LIFE TECHNOLOGIES INC (US) 1990-01-08 EP claimed
EP-0287652-A1 SERUM-FREE MEDIUM FOR THE PROLIFERATION OF LYMPHOKINE-ACTIVATED KILLER CELLS. LIFE TECHNOLOGIES INC (US) 1988-10-26 EP claimed
WO-1988002774-A1 SERUM-FREE MEDIUM FOR THE PROLIFERATION OF LYMPHOKINE-ACTIVATED KILLER CELLS LIFE TECHNOLOGIES, INC. (US) 1988-04-21 WO claimed
US-7635798-B2 Nucleic acid compositions conferring altered metabolic characteristics DOW AGROSCIENCES, LLC (US) 2009-12-22 US disclosed
US-20050091708-A1 Nucleic acid compositions conferring altered metabolic characteristics DOW AGROSCIENCES LLC 2005-04-28 US disclosed
WO-2003020936-A1 NUCLEIC ACID COMPOSITIONS CONFERRING ALTERED METABOLIC CHARACTERISTICS THE DOW CHEMICAL COMPANY (US) 2003-03-13 WO disclosed
EP-0287652-B1 SERUM-FREE MEDIUM FOR THE PROLIFERATION OF LYMPHOKINE-ACTIVATED KILLER CELLS LIFE TECHNOLOGIES INC (US) 1994-01-12 EP disclosed
EP-0287652-A4 SERUM-FREE MEDIUM FOR THE PROLIFERATION OF LYMPHOKINE-ACTIVATED KILLER CELLS. LIFE TECHNOLOGIES INC (US) 1990-01-08 EP disclosed
EP-0287652-A1 SERUM-FREE MEDIUM FOR THE PROLIFERATION OF LYMPHOKINE-ACTIVATED KILLER CELLS. LIFE TECHNOLOGIES INC (US) 1988-10-26 EP disclosed
WO-1988002774-A1 SERUM-FREE MEDIUM FOR THE PROLIFERATION OF LYMPHOKINE-ACTIVATED KILLER CELLS LIFE TECHNOLOGIES, INC. (US) 1988-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050091708-A1 Nucleic acid compositions conferring altered metabolic characteristics FADS1, FASN, FADS2 USP2 4664/4885ALDH1A1 1580/4885CNR1 1634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.