Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.37 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.37 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5936415 | 0.83 | SPHK1 (0.51) | USP2LPAR1LPAR3LPAR2LPAR6 | |
| SCHEMBL6151119 | 0.83 | USP2 (0.43) | USP2MGAMLMNAKDM4E | |
| SCHEMBL29249582 | 0.83 | USP2 (0.43) | USP2MGAMLMNAKDM4E | |
| SCHEMBL6150703 | 0.83 | USP2 (0.43) | USP2MGAMLMNAKDM4E | |
| SCHEMBL4551078 | 0.81 | USP2 (0.41) | USP2MGAMALDH1A1CNR1CNR2 | |
| SCHEMBL10466712 | 0.78 | MGAM (0.52) | USP2MGAMALDH1A1CNR1CNR2 | |
| SCHEMBL27592379 | 0.78 | MGAM (0.52) | USP2MGAMALDH1A1CNR1CNR2 | |
| SCHEMBL8105632 | 0.78 | USP2 (0.42) | USP2MGAMALDH1A1DNM1CYP2D6 | |
| SCHEMBL7455637 | 0.78 | USP2 (0.42) | USP2MGAMALDH1A1DNM1CYP2D6 | |
| SCHEMBL8345461 | 0.77 | CES2 (0.44) | LMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060154984-A1 | Therapeutic use of acyl glycerols and the nitrogen- and sulphur- containing analogues thereof | GENFIT (FR) | 2006-07-13 | — | — | US | claimed |
| EP-1596845-A1 | THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF | Genfit (FR) | 2005-11-23 | — | — | EP | claimed |
| WO-2004073698-A1 | THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF | GENFIT (FR) | 2004-09-02 | — | — | WO | claimed |
| US-7375135-B2 | Fatty acid derivatives; preparation and uses thereof | GENFIT (FR) | 2008-05-20 | — | — | US | disclosed |
| EP-1673338-B1 | FATTY ACID COMPOUNDS, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-09-19 | — | — | EP | disclosed |
| US-20060252827-A1 | Therapeutic use of of acyglycerols and the nitrogen-and sulphur-containing analogues thereof | GENFIT (FR) | 2006-11-09 | — | — | US | disclosed |
| US-20060154984-A1 | Therapeutic use of acyl glycerols and the nitrogen- and sulphur- containing analogues thereof | GENFIT (FR) | 2006-07-13 | — | — | US | disclosed |
| EP-1673338-A1 | FATTY ACID COMPOUNDS, PREPARATION AND USES THEREOF | Genfit (FR) | 2006-06-28 | — | — | EP | disclosed |
| EP-1596845-A1 | THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF | Genfit (FR) | 2005-11-23 | — | — | EP | disclosed |
| EP-1587508-A1 | THERAPEUTIC USE OF ACYLGLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEREOF | Genfit (FR) | 2005-10-26 | — | — | EP | disclosed |
| US-20040192908-A1 | Fatty acid compounds, preparation and uses thereof | GENFIT (FR) | 2004-09-30 | — | — | US | disclosed |
| WO-2004073698-A1 | THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF | GENFIT (FR) | 2004-09-02 | — | — | WO | disclosed |
| WO-2004069241-A1 | THERAPEUTIC USE OF ACYLGLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEREOF | GENFIT (FR) | 2004-08-19 | — | — | WO | disclosed |
| WO-2003014073-A1 | FATTY ACID COMPOUNDS, PREPARATION AND USES THEREOF | GENFIT (FR) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252827-A1 | Therapeutic use of of acyglycerols and the nitrogen-and sulphur-containing analogues thereof | SGMS2, SGMS1, AGK | USP2 2389/4885MGAM 1819/4885ALDH1A1 3402/4885 |
| US-20040192908-A1 | Fatty acid compounds, preparation and uses thereof | FASN, FFAR1, PLIN5 | USP2 4008/4885MGAM 2415/4885ALDH1A1 1220/4885 |
| US-20060154984-A1 | Therapeutic use of acyl glycerols and the nitrogen- and sulphur- containing analogues thereof | AGPAT5, HAGH, AGPAT2 | USP2 1833/4885MGAM 1085/4885ALDH1A1 1482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.