Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | FAAH | O00519 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4413334 | 0.86 | SIGMAR1 (0.74) | SIGMAR1GAATSHRFAAHALDH1A1 | |
| SCHEMBL4551093 | 0.85 | SIGMAR1 (0.72) | SIGMAR1GAATSHRFAAHALDH1A1 | |
| SCHEMBL27615815 | 0.85 | SIGMAR1 (0.68) | SIGMAR1GAATSHRFAAHALDH1A1 | |
| SCHEMBL1383233 | 0.85 | SIGMAR1 (0.68) | SIGMAR1GAATSHRFAAHALDH1A1 | |
| SCHEMBL28186295 | 0.84 | SIGMAR1 (0.90) | SIGMAR1GAATSHRFAAHALDH1A1 | |
| SCHEMBL20804357 | 0.84 | SIGMAR1 (0.90) | SIGMAR1GAATSHRFAAHALDH1A1 | |
| SCHEMBL19049381 | 0.81 | ALDH1A1 (0.71) | SIGMAR1GAAFAAHALDH1A1KDM4E | |
| SCHEMBL2931334 | 0.81 | SIGMAR1 (0.74) | SIGMAR1GAAFAAHALDH1A1KDM4E | |
| SCHEMBL4552412 | 0.80 | CYP2D6 (0.54) | GAATSHRFAAHALDH1A1KDM4E | |
| SCHEMBL13673066 | 0.79 | SIGMAR1 (0.62) | SIGMAR1GAATSHRFAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608249-B2 | Enhanced substrate imaging by reversible binding to a paramagnetic complex | BRACCO IMAGING S.P.A. (IT) | 2009-10-27 | — | — | US | disclosed |
| EP-1434768-B1 | ENHANCED SUBSTRATE IMAGING BY REVERSIBLE BINDING TO A PARAMAGNETIC COMPLEX | BRACCO IMAGING SPA (IT) | 2009-08-12 | — | — | EP | disclosed |
| US-20040258618-A1 | Enhanced substrate imaging by reversible binding to a paramagnetic complex | BRACCO IMAGING S.P.A. (IT) | 2004-12-23 | — | — | US | disclosed |
| EP-1434768-A1 | ENHANCED SUBSTRATE IMAGING BY REVERSIBLE BINDING TO A PARAMAGNETIC COMPLEX | Bracco Imaging S.p.A. (IT) | 2004-07-07 | — | — | EP | disclosed |
| WO-2003033479-A1 | ENHANCED SUBSTRATE IMAGING BY REVERSIBLE BINDING TO A PARAMAGNETIC COMPLEX | BRACCO IMAGING S.P.A. (IT) | 2003-04-24 | — | — | WO | disclosed |