⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL861621 | 0.94 | PRCP (0.36) | — | |
| SCHEMBL9327557 | 0.92 | PRCP (0.38) | — | |
| Nitric Acid SCHEMBL10592938 | 0.82 | MEN1 (0.32) | — | |
| SCHEMBL27829276 | 0.79 | DRD2 (0.32) | — | |
| SCHEMBL16861251 | 0.78 | — | — | |
| SCHEMBL5580304 | 0.77 | HTR1A (0.44) | — | |
| SCHEMBL9685949 | 0.76 | — | — | |
| SCHEMBL13716449 | 0.75 | — | — | |
| SCHEMBL8436147 | 0.75 | POLB (0.42) | — | |
| SCHEMBL11300057 | 0.75 | POLB (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160222014-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2016-08-04 | — | — | US | claimed |
| WO-2015038417-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2015-03-19 | — | — | WO | claimed |
| US-7605284-B2 | Process for preparing organically modified polyorganosiloxanes | GOLDSCHMIDT GMBH (DE) | 2009-10-20 | — | — | US | claimed |
| US-20070100153-A1 | PROCESS FOR PREPARING ORGANICALLY MODIFIED POLYORGANOSILOXANES | GOLDSCHMIDT GMBH (DE) | 2007-05-03 | — | — | US | claimed |
| JP-6072999-A | — | — | None | — | — | JP | disclosed |
| US-20160222014-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2016-08-04 | — | — | US | disclosed |
| WO-2015038417-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2015-03-19 | — | — | WO | disclosed |
| US-7605284-B2 | Process for preparing organically modified polyorganosiloxanes | GOLDSCHMIDT GMBH (DE) | 2009-10-20 | — | — | US | disclosed |
| EP-1532109-B1 | PYRROLIDINE DERIVATIVES AS OXYTOCIN ANTAGONISTS | MERCK SERONO SA (CH) | 2009-09-09 | — | — | EP | disclosed |
| EP-1986614-A2 | PROTEIN HYDROLYSATE EXCIPIENTS | Wyeth (US) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007097936-A2 | PROTEIN HYDROLYSATE EXCIPIENTS | WYETH (US) | 2007-08-30 | — | — | WO | disclosed |
| US-20070100153-A1 | PROCESS FOR PREPARING ORGANICALLY MODIFIED POLYORGANOSILOXANES | GOLDSCHMIDT GMBH (DE) | 2007-05-03 | — | — | US | disclosed |
| WO-2004005249-A1 | PYRROLIDINE DERIVATIVES AS OXYTOCIN ANTAGONISTS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2004-01-15 | — | — | WO | disclosed |
| EP-1339677-A1 | AMINOALKYLPYRROLIDINE SEROTONIN RECEPTOR LIGANDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND METHODS FOR THEIR SYNTHESIS | Warner-Lambert Company LLC (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002036560-A1 | AMINOALKYLPYRROLIDINE SEROTONIN RECEPTOR LIGANDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND METHODS FOR THEIR SYNTHESIS | WARNER-LAMBERT COMPANY LLC (US) | 2002-05-10 | — | — | WO | disclosed |
| US-6333435-B1 | CHIRAL LIGAND FOR CATALYTIC ASYMMETRIC INDUCTION | MERCK & CO., INC. | 2001-12-25 | — | — | US | disclosed |
| WO-1995032934-A1 | PROCESS OF SYNTHESIZING BINAPHTHYL DERIVATIVES | MERCK & CO., INC. (US) | 1995-12-07 | — | — | WO | disclosed |
| US-5399771-A | Process of synthesizing binaphthyl derivatives | MERCK & CO., INC. (US) | 1995-03-21 | — | — | US | disclosed |
| JP-H0672999-A | PRODUCTION OF AMINOALKYLPYRROLIDINE COMPOUND | FUJISAWA PHARMACEUT CO LTD | 1994-03-15 | — | — | JP | disclosed |
| US-5081260-A | 3-(2-OXO-1-PYRROLIDINYL)-PROPYLSILANES AND METHOD FOR PREPARING THE SILANE COMPOUNDS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |