Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 15/20 | 0.44 |
| ▸ | DRD2 | P14416 | 12/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986246 | 0.87 | PRCP (0.44) | HTR1ADRD2PRCP | |
| SCHEMBL9685949 | 0.79 | — | — | |
| SCHEMBL31247515 | 0.79 | HTR1A (0.48) | HTR1ADRD2PRCP | |
| SCHEMBL3423910 | 0.77 | — | — | |
| SCHEMBL8587021 | 0.77 | — | — | |
| SCHEMBL4551362 | 0.77 | — | — | |
| SCHEMBL5143116 | 0.77 | — | — | |
| SCHEMBL2852701 | 0.77 | — | — | |
| SCHEMBL9824237 | 0.77 | HTR1A (0.40) | HTR1ADRD2PRCP | |
| SCHEMBL7941591 | 0.77 | HTR1A (0.38) | HTR1ADRD2PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809301-A2 | PREPARATION OF 2'FLUORO-2'-ALKYL-SUBSTITUTED OR OTHER OPTIONALLY SUBSTITUTED RIBOFURANOSYL PYRIMIDINES AND PURINES AND THEIR DERIVATIVES | Pharmasset, Inc. (US) | 2007-07-25 | — | — | EP | claimed |
| US-20060122146-A1 | Preparation of 2'-fluoro-2'-alkyl-substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives | GILEAD SCIENCES, INC. | 2006-06-08 | — | — | US | claimed |
| WO-2006031725-A2 | PREPARATION OF 2'FLUORO-2'- ALKYL- SUBSTITUTED OR OTHER OPTIONALLY SUBSTITUTED RIBOFURANOSYL PYRIMIDINES AND PURINES AND THEIR DERIVATIVES | PHARMASSET, INC. (US) | 2006-03-23 | — | — | WO | claimed |
| EP-3109244-A2 | PREPARATION OF 2'FLUORO-2'-ALKYL-SUBSTITUTED OR OTHER OPTIONALLY SUBSTITUTED RIBOFURANOSYL PYRIMIDINES AND PURINES AND THEIR DERIVATIVES | Gilead Pharmasset LLC (US) | 2016-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122146-A1 | Preparation of 2'-fluoro-2'-alkyl-substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives | NSUN2, FBL, RNGTT | HTR1A 2532/4885DRD2 870/4885PRCP 1615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.