Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11726250 | 0.92 | ALDH1A1 (0.50) | POLBNPSR1HTTLMNACYP2D6 | |
| SCHEMBL19880106 | 0.88 | POLB (0.39) | POLBNPSR1HTTLMNAIDO1 | |
| SCHEMBL11749783 | 0.86 | MAPT (0.44) | POLBNPSR1HTTLMNACYP2D6 | |
| SCHEMBL29911655 | 0.79 | POLB (0.46) | POLBNPSR1HTTLMNACYP2D6 | |
| SCHEMBL583081 | 0.79 | CCNE2 (0.44) | NPSR1LMNACYP2D6TSHRMAPT | |
| SCHEMBL3076978 | 0.79 | TAAR1 (0.48) | NPSR1LMNACYP2D6TSHRIDO1 | |
| SCHEMBL23456183 | 0.78 | MAPT (0.43) | POLBHTTLMNAMAPTHPGD | |
| SCHEMBL12177981 | 0.78 | POLB (0.38) | POLBNPSR1HTTLMNACYP2D6 | |
| SCHEMBL11691246 | 0.77 | NPSR1 (0.41) | NPSR1LMNACYP2D6TSHRIDO1 | |
| SCHEMBL1162021 | 0.77 | NPSR1 (0.62) | POLBNPSR1LMNACYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023112038-A1 | NEUTROPHIL EXOCYTOSIS INHIBITORS | IMMUNYX PHARMA LTD. (IL) | 2023-06-22 | — | — | WO | disclosed |
| CN-111556864-B | Compounds with stabilizing effect, preparation method and use thereof, compositions containing same and method for stabilizing organic components | 弗劳恩霍弗应用研究促进协会 | 2022-07-08 | — | — | CN | disclosed |
| CN-114606012-A | Polymerizable liquid crystal material and polymerized liquid crystal film | 默克专利股份有限公司 | 2022-06-10 | — | — | CN | disclosed |
| EP-3218350-B1 | PROCESS FOR FORMING AMINE BY DIRECT AMINATION REACTION | RHODIA OPERATIONS (FR) | 2022-01-05 | — | — | EP | disclosed |
| CN-113677781-A | Metalworking fluids containing branched alcohol propoxylates | 巴斯夫欧洲公司 | 2021-11-19 | — | — | CN | disclosed |
| CN-111032826-A | Polymerizable LC medium and polymer film with flat light dispersion | 默克专利股份有限公司 | 2020-04-17 | — | — | CN | disclosed |
| CN-106456581-A | Trka kinase inhibitors, compositions and methods thereof | 默沙东公司 | 2017-02-22 | — | — | CN | disclosed |
| US-7504510-B2 | Graftable hindered amine light stabilizers | CIBA SPECIALTY CHEMICALS CORP. (US) | 2009-03-17 | — | — | US | disclosed |
| US-20060173107-A1 | Graftable hindered amine light stabilizers | CIBA SPECIALTY CHEMICALS CORP. | 2006-08-03 | — | — | US | disclosed |
| EP-0327318-B1 | Heat-sensitive recording materials | FUJI PHOTO FILM CO LTD (JP) | 1995-07-19 | — | — | EP | disclosed |
| EP-0327318-A2 | Heat-sensitive recording materials | FUJI PHOTO FILM CO., LTD. (JP) | 1989-08-09 | — | — | EP | disclosed |
| EP-0288240-A2 | Heat-sensitive diazo recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1988-10-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173107-A1 | Graftable hindered amine light stabilizers | IDO1, MAOA, TPH1 | POLB 1026/4885NPSR1 714/4885HTT 600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.