Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410231 | 0.94 | BRAF (0.48) | BRAFRAF1 | |
| SCHEMBL4417865 | 0.94 | BRAF (0.47) | BRAFRAF1 | |
| SCHEMBL4408526 | 0.90 | RAF1 (0.57) | BRAFRAF1 | |
| SCHEMBL4565118 | 0.88 | RAF1 (0.56) | BRAFRAF1 | |
| SCHEMBL4551380 | 0.87 | BRAF (0.46) | BRAFRAF1 | |
| SCHEMBL4552241 | 0.87 | RAF1 (0.63) | BRAFRAF1 | |
| SCHEMBL4412693 | 0.86 | RAF1 (0.49) | BRAFRAF1 | |
| SCHEMBL5593266 | 0.86 | RAB9A (0.50) | BRAFRAF1 | |
| SCHEMBL4551893 | 0.86 | RAF1 (0.54) | BRAFRAF1 | |
| SCHEMBL4420764 | 0.84 | BRAF (0.61) | BRAFRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035005-A2 | THERAPY USING CYTOKINE INHIBITORS | Kemia, INC. (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007146712-A2 | THERAPY USING CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |