Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 4/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL406820 | 0.90 | HPGD (0.48) | HPGDGPR119RECQLEPHX1STS | |
| SCHEMBL1514778 | 0.86 | EPHX1 (0.52) | HPGDGPR119RECQLEPHX1STS | |
| SCHEMBL1088787 | 0.85 | GPR119 (0.46) | HPGDGPR119RECQLEPHX1STS | |
| SCHEMBL16497005 | 0.79 | HPGD (0.48) | HPGDGPR119RECQLEPHX1STS | |
| SCHEMBL7512359 | 0.79 | GPR119 (0.56) | HPGDGPR119RECQLEPHX1 | |
| SCHEMBL4551353 | 0.78 | USP2 (0.43) | GPR119USP2SMN1; SMN2 | |
| SCHEMBL390009 | 0.78 | GPR119 (0.49) | GPR119STS | |
| SCHEMBL20128944 | 0.77 | GPR119 (0.57) | HPGDGPR119RECQL | |
| SCHEMBL8151168 | 0.77 | GPR119 (0.55) | HPGDGPR119RECQLEPHX1USP2 | |
| SCHEMBL25176980 | 0.77 | NR1H2 (0.43) | HPGDGPR119RECQLEPHX1STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005375-A1 | ACETYL COENZYME A CARBOXYLASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-01-01 | — | — | US | disclosed |
| WO-2008121592-A2 | ACETYL COENZYME A CARBOXYLASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005375-A1 | ACETYL COENZYME A CARBOXYLASE INHIBITORS | ACACA, ACACB, ACAT1 | HPGD 705/4885GPR119 2816/4885RECQL 1818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.