Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | RORC | P51449 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | RORA | P35398 | 1/20 | 0.39 |
| ▸ | RORB | Q92753 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4384762 | 0.80 | HSD11B1 (0.46) | ALDH1A1KDM4ETDP1RECQLCYP3A4 | |
| SCHEMBL4382904 | 0.77 | LMNA (0.45) | ALDH1A1KDM4EGAACYP2D6CYP2C19 | |
| SCHEMBL13588928 | 0.72 | CARM1 (0.38) | NPSR1RORCALDH1A1KDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL4380931 | 0.71 | CTSL (0.38) | NPSR1RORCALDH1A1KDM4ETDP1 | |
| SCHEMBL4395579 | 0.70 | KMT2A (0.51) | ALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL17986303 | 0.69 | IDO1 (0.66) | ALDH1A1KDM4ETDP1IDO1KMT2A | |
| SCHEMBL4679010 | 0.69 | IDO1 (0.56) | NPSR1ALDH1A1KDM4ETDP1RECQL | |
| SCHEMBL4390793 | 0.68 | MEN1 (0.45) | ALDH1A1GAACYP2C9CYP2C19KMT2A | |
| SCHEMBL4379552 | 0.65 | LMNA (0.52) | ALDH1A1GAACYP2C9KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9266923 | 0.65 | IDO1 (0.43) | ALDH1A1KDM4EIDO1CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2040698-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008008398-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2008-01-17 | — | — | WO | disclosed |