Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PKLR | P30613 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GCK | P35557 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21925711 | 0.87 | POLB (0.59) | KMT2AKDM4EGAAHTTPOLB | |
| SCHEMBL22051334 | 0.78 | ALDH1A1 (0.53) | KCNH2NPC1PKMPKLRRAB9A | |
| SCHEMBL6036911 | 0.77 | PKM (0.77) | KMT2ANPC1PKMPKLRRAB9A | |
| SCHEMBL1359572 | 0.76 | CHRNB2 (0.58) | KMT2ANPC1HTTSMN1; SMN2MEN1 | |
| SCHEMBL16301360 | 0.75 | KDM4E (0.51) | KMT2AKDM4EGAAHTTSMN1; SMN2 | |
| Ethylene SCHEMBL8382024 | 0.75 | PKM (0.73) | KMT2ANPC1PKMPKLRRAB9A | |
| SCHEMBL6977881 | 0.74 | GPBAR1 (0.73) | PKMKDM4EHTTSMN1; SMN2POLB | |
| SCHEMBL22051298 | 0.73 | HTR2B (0.51) | KMT2AKCNH2RAB9AGAAHTT | |
| SCHEMBL22050484 | 0.73 | HTR2B (0.51) | KMT2AKCNH2RAB9AGAAHTT | |
| SCHEMBL2120289 | 0.73 | KDM4E (0.53) | KMT2AKCNH2NPC1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2040698-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008008398-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2008-01-17 | — | — | WO | disclosed |