SCHEMBL455177

SCHEMBL455177

CCc1ccc[c]c1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11232564 0.83 GABRA1 (0.37)
SCHEMBL27306793 0.77
SCHEMBL16952915 0.77
SCHEMBL11444426 0.77 LIPG (0.47)
SCHEMBL27930849 0.76 TDP1 (0.34)
SCHEMBL64051 0.74 GABRA1 (0.41)
SCHEMBL218223 0.74
SCHEMBL6194301 0.74 TDP1 (0.33)
SCHEMBL19405501 0.74 GABRA1 (0.31)
SCHEMBL19405390 0.74 SLC6A2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2903440-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES Bayer CropScience AG (DE) 2015-08-12 EP claimed
WO-2014053450-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2014-04-10 WO claimed
EP-2900645-B1 HERBICIDAL AND FUNGICIDAL 3-PHENYLISOXAZOLIN DERIVATIVES BAYER CROPSCIENCE AG (DE) 2019-08-21 EP disclosed
EP-3045450-B1 INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS SUMITOMO CHEMICAL CO (JP) 2018-02-07 EP disclosed
US-9585392-B2 3-phenylisoxazolin derivatives with herbicidal action BAYER CROPSCIENCE AG (DE) 2017-03-07 US disclosed
CN-104277004-B Prepare method and its intermediate of pyridazinone compound 住友化学株式会社 2016-08-24 CN disclosed
CN-104326952-B Prepare method and its intermediate of pyridazinone compound 住友化学株式会社 2016-08-24 CN disclosed
EP-3045450-A1 INTERMEDIATE COMPOUNDS IN A PROCESS FOR PRODUCING PYRIDAZINONE COMPOUNDS SUMITOMO CHEMICAL CO., LTD. (JP) 2016-07-20 EP disclosed
EP-2614053-B1 METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATES THEREOF SUMITOMO CHEMICAL CO (JP) 2016-03-23 EP disclosed
WO-2015144652-A2 HETEROCYCLIC COMPOUNDS FOR THE CONTROL OF UNWANTED MICROORGANISMS BAYER CROPSCIENCE AG (DE) 2015-10-01 WO disclosed
US-20150245615-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION BAYER CROPSCIENCE AG (DE) 2015-09-03 US disclosed
WO-2000017157-A1 OPTICALLY ACTIVE SUBSTITUTED N-ARYL-O-ARYLOXYALKYL-CARBAMATES BAYER AKTIENGESELLSCHAFT (DE) 2000-03-30 WO disclosed
EP-0980867-A1 KETONE DERIVATIVES AND MEDICINAL USE THEREOF TORAY INDUSTRIES, INC. (JP) 2000-02-23 EP disclosed
CN-1242771-A Ketone derivatives and medicinal use thereof TORAY INDUSTRIES (JP) 2000-01-26 CN disclosed
CN-1242770-A Cyclic ketone derivative and pharmaceutical use thereof TORAY INDUSTRIES (JP) 2000-01-26 CN disclosed
EP-0962456-A1 CYCLIC KETONE DERIVATIVE AND PHARMACEUTICAL USE THEREOF TORAY INDUSTRIES, INC. (JP) 1999-12-08 EP disclosed
WO-1997033862-A1 PESTICIDAL HYDRAZIDE DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. (US) 1997-09-18 WO disclosed
EP-0404029-B1 Substantially odor free, UV curable organopolysiloxane release coating compositions and coating method GEN ELECTRIC (US) 1994-02-16 EP disclosed
US-4994299-A Epoxyhaloarylaklsiloxane with polyaryloniumhexafluorometalloid salt photoinitiator GENERAL ELECTRIC COMPANY (US) 1991-02-19 US disclosed
EP-0404029-A1 Substantially odor free, UV curable organopolysiloxane release coating compositions and coating method GENERAL ELECTRIC COMPANY (US) 1990-12-27 EP disclosed