SCHEMBL64051

SCHEMBL64051

CCc1[c]cccc1CC

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.41
GABRB2 P47870 4/20 0.41
MGLL Q99685 1/20 0.38
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30
GRIN2B Q13224 1/20 0.30
GRIN2C Q14957 1/20 0.30
GRIN3A Q8TCU5 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28322624 0.92 GABRA1 (0.40) GABRA1GABRB2MGLLCYP2D6
SCHEMBL27407076 0.85 GABRA1 (0.37) GABRA1GABRB2MGLLCYP2D6MAPT
SCHEMBL816308 0.85 GABRA1 (0.37) GABRA1GABRB2MGLLCYP2D6
SCHEMBL10882541 0.85 GABRA1 (0.41) GABRA1GABRB2MGLLCYP2D6MAPT
SCHEMBL6339207 0.85 MGLL (0.34) GABRA1GABRB2MGLL
SCHEMBL16953556 0.85 GABRA1 (0.37) GABRA1GABRB2MGLL
SCHEMBL27379450 0.85 PNMT (0.35) GABRA1GABRB2MGLL
SCHEMBL2636667 0.85 GABRA1 (0.37) GABRA1GABRB2MGLLCYP2D6
SCHEMBL28072585 0.82 L3MBTL1 (0.39) GABRA1GABRB2MGLLMAPTL3MBTL1
SCHEMBL815623 0.81 GABRA1 (0.34) GABRA1GABRB2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4137 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117831652-A Prediction method of olefin hydroformylation positive-to-negative ratio 上海华谊控股集团有限公司 2024-04-05 CN claimed
CN-117658082-A Preparation method of wurtzite nano-sheet and wurtzite nano-sheet 利亚德光电股份有限公司 2024-03-08 CN claimed
CN-114206886-B Gold (III) compound, method for preparing the same, and organic light emitting device using the same 广东聚华印刷显示技术有限公司 2024-02-27 CN claimed
CN-117551134-A Complex and preparation method and application thereof 南京佳诺霖光电科技有限公司 2024-02-13 CN claimed
WO-2024022413-A1 DIVALENT METAL COMPLEX, PREPARATION METHOD THEREFOR AND USE THEREOF, AND ORGANIC OPTOELECTRONIC DEVICE 中国石油化工股份有限公司 2024-02-01 WO claimed
CN-117466944-A Divalent metal complex, preparation method and application thereof, and organic photoelectric device 中国石油化工股份有限公司 2024-01-30 CN claimed
CN-116655699-A Bivalent platinum complex white phosphorus light material and device application thereof 南京佳诺霖光电科技有限公司 2023-08-29 CN claimed
CN-116332978-B Organic compound, preparation method thereof and organic electroluminescent device comprising organic compound 吉林奥来德光电材料股份有限公司 2023-08-29 CN claimed
EP-3575281-B1 DIAMINE COMPOUND, AND POLYIMIDE COMPOUND AND MOLDED ARTICLE IN WHICH SAID DIAMINE COMPOUND IS USED WINGO TECH CO LTD (JP) 2023-08-23 EP claimed
CN-116574136-A Bivalent platinum complex and preparation method and application thereof 南京佳诺霖光电科技有限公司 2023-08-11 CN claimed
EP-0232224-B1 PIPERIDINE COMPOUNDS CIBA-GEIGY AG (CH) 1992-11-25 EP claimed
US-5159074-A AMINOMETHANEPHOSPHONIC ACID ARYL ESTERS, A PROCESS FOR THEIR PRODUCTION AND THEIR USE BAYER AKTIENGESELLSCHAFT (DE) 1992-10-27 US claimed
WO-1992017469-A2 N-ARYLHETEROARYLALKYL IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS G.D. SEARLE & CO. (US) 1992-10-15 WO claimed
EP-0508393-A1 N-arylheteroarylalkyl imidazol-2-one compounds for treatment of circulatory disorders G.D. Searle & Co. (US) 1992-10-14 EP claimed
WO-1992014697-A1 SUBSTITUTED GUANIDINES AND DERIVATIVES THEREOF AS MODULATORS OF NEUROTRANSMITTER RELEASE AND NOVEL METHODOLOGY FOR IDENTIFYING NEUROTRANSMITTER RELEASE BLOCKERS CAMBRIDGE NEUROSCIENCE, INC. (US) 1992-09-03 WO claimed
US-4626556-A LADDER POLYMERS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1986-12-02 US claimed
US-4567197-A THORMBOXANE A2 ANTAGONISTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-01-28 US claimed
US-4133648-A ALKANEDIOLS GULF RESEARCH & DEVELOPMENT COMPANY (US) 1979-01-09 US claimed
US-4009206-A CHOLESTEROL LOWERING AGENTS MURAI HIROMU 1977-02-22 US claimed
US-3948898-A HYPOTENSIVES, SEDATIVES, ANTIARRHYTHMICS, BRADYCARDIACS BOEHRINGER INGELHEIM GMBH (DT) 1976-04-06 US claimed