⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28844832 | 0.83 | CA12 (0.38) | — | |
| SCHEMBL2310735 | 0.80 | CTSK (0.33) | — | |
| SCHEMBL5008278 | 0.78 | TRPV1 (0.30) | — | |
| SCHEMBL29197394 | 0.77 | OPRM1 (0.38) | — | |
| SCHEMBL29197374 | 0.77 | OPRM1 (0.38) | — | |
| SCHEMBL28501155 | 0.77 | OPRM1 (0.38) | — | |
| SCHEMBL29197496 | 0.77 | OPRM1 (0.38) | — | |
| SCHEMBL18095456 | 0.77 | — | — | |
| SCHEMBL379681 | 0.75 | CYP3A4 (0.31) | — | |
| SCHEMBL3482772 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230042176-A1 | METHOD FOR TREATING ANGELMAN SYNDROME AND RELATED DISORDERS | NAT UNIV SINGAPORE (SG) | 2023-02-09 | — | — | US | disclosed |
| EP-4076471-A1 | METHOD FOR TREATING ANGELMAN SYNDROME AND RELATED DISORDERS | National University of Singapore (SG) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021126087-A1 | METHOD FOR TREATING ANGELMAN SYNDROME AND RELATED DISORDERS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2021-06-24 | — | — | WO | disclosed |
| US-8981080-B2 | Silane-modified cationized polymeric compound and process for production thereof | LION CORPORATION (JP) | 2015-03-17 | — | — | US | disclosed |
| EP-2182009-B1 | METHOD OF PRODUCING OF SILANE-MODIFIED CATIONIZED CELLULOSE | LION CORP (JP) | 2013-11-13 | — | — | EP | disclosed |
| US-8569263-B2 | Method of producing silane-modified cationized cellulose | LION CORPORATION (JP) | 2013-10-29 | — | — | US | disclosed |
| US-20120065388-A1 | SILANE-MODIFIED CATIONIZED POLYMERIC COMPOUND AND PROCESS FOR PRODUCTION THEREOF | LION CORPORATION (JP) | 2012-03-15 | — | — | US | disclosed |
| US-20110218336-A1 | METHOD OF PRODUCING SILANE-MODIFIED CATIONIZED CELLULOSE | LION CORPORATION (JP) | 2011-09-08 | — | — | US | disclosed |
| US-20110212044-A1 | CLEANSER COMPOSITION | LION CORPORATION (JP) | 2011-09-01 | — | — | US | disclosed |
| EP-2351553-A1 | CLEANSER COMPOSITION | Lion Corporation (JP) | 2011-08-03 | — | — | EP | disclosed |
| EP-2182009-A1 | PROCESS FOR PRODUCTION OF SILANE-MODIFIED CATIONIZED CELLULOSE | Lion Corporation (JP) | 2010-05-05 | — | — | EP | disclosed |
| US-5536584-A | SEMICONDUCTOR INTEGRATED CIRCUIT, TRANSISTOR AND A THIN FILM MULTILEVEL WIRING BOARD USES SURFACE PROTECTIVE COATING OF POLYIMIDE | HITACHI, LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5272247-A | Polyimide precursor, cured product thereof, and processes for producing them | HITACHI, LTD. (JP) | 1993-12-21 | — | — | US | disclosed |