SCHEMBL4552047

SCHEMBL4552047

C=CC(C(=O)NN)c1ncc[nH]1

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.35
MMP3 P08254 1/20 0.35
MMP7 P09237 1/20 0.35
CSNK1A1 P48729 1/20 0.35
TYRO3 Q06418 1/20 0.35
DYRK1B Q9Y463 1/20 0.35
FPR2 P25090 9/20 0.35
ADRA2A P08913 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
F2RL1 P55085 2/20 0.32
FDPS P14324 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11381591 0.80 KDM4E (0.38) MMP1MMP3MMP7CSNK1A1TYRO3
SCHEMBL4411652 0.76 MMP1 (0.43) MMP1MMP3MMP7CSNK1A1TYRO3
SCHEMBL2133067 0.69
SCHEMBL167809 0.69
SCHEMBL11378231 0.68 ALDH1A1 (0.36) CSNK1A1TYRO3DYRK1BFPR2ADRA2A
SCHEMBL6158532 0.68
SCHEMBL8958487 0.67 F2RL1 (0.36) F2RL1
SCHEMBL7112560 0.66 FPR2 (0.38) MMP1MMP3MMP7FPR2ADRA2A
SCHEMBL29029820 0.66 SMN1; SMN2 (0.38) MMP1MMP3MMP7CSNK1A1TYRO3
SCHEMBL7198925 0.66 FPR2 (0.52) MMP1MMP3MMP7FPR2ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed