Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 15/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 2/20 | 0.40 |
| ▸ | SI | P14410 | 2/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4552338 | 0.90 | CCR5 (0.47) | CCR5KCNH2 | |
| SCHEMBL4023399 | 0.84 | CCR5 (0.43) | CCR5KCNH2 | |
| SCHEMBL13946615 | 0.73 | ATM (0.42) | CCR5 | |
| SCHEMBL4206072 | 0.73 | ATM (0.42) | CCR5KCNH2 | |
| SCHEMBL13969503 | 0.73 | KDM4E (0.45) | CCR5 | |
| SCHEMBL6505071 | 0.72 | ALDH1A1 (0.55) | — | |
| SCHEMBL4597864 | 0.72 | ALDH1A1 (0.55) | — | |
| SCHEMBL5576143 | 0.72 | ALDH1A1 (0.55) | — | |
| SCHEMBL20144687 | 0.71 | GAA (0.56) | MGAMSIKCNQ3KCNQ2 | |
| SCHEMBL20144711 | 0.70 | GAA (0.54) | MGAMSIKCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088860-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008070758-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |