Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TTR | P02766 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.47 |
| ▸ | CBR1 | P16152 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3438989 | 0.83 | MAPT (0.62) | FFAR1MAPTTTRHPGDSLC6A3 | |
| SCHEMBL11649803 | 0.83 | SLC6A4 (0.57) | FFAR1MAPTTTRHPGDSLC6A3 | |
| SCHEMBL11007589 | 0.80 | FFAR1 (0.54) | FFAR1MAPTTTRLMNAMEN1 | |
| SCHEMBL7106722 | 0.79 | MAOA (0.52) | MAPTHPGDLMNACYP1A2CYP2C9 | |
| SCHEMBL9339622 | 0.79 | HPGD (0.48) | FFAR1MAPTTTRHPGDSLC6A3 | |
| SCHEMBL3469104 | 0.77 | TTR (0.61) | FFAR1MAPTTTRHPGDSLC6A3 | |
| SCHEMBL554810 | 0.77 | MAOA (0.61) | FFAR1MAPTTTRHPGDSLC6A3 | |
| SCHEMBL2092929 | 0.77 | FFAR1 (0.53) | FFAR1MAPTTTRHPGDSLC6A3 | |
| SCHEMBL8502158 | 0.77 | FFAR1 (0.56) | FFAR1MAPTTTRHPGDSLC6A3 | |
| SCHEMBL16705542 | 0.77 | HTR2A (0.55) | FFAR1MAPTTTRHPGDSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1299354-B1 | FACTOR VIIA INHIBITORY (THIO)UREA DERIVATIVES, THEIR PREPARATION AND THEIR USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-07-22 | — | — | EP | claimed |