Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 8/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187923 | 0.88 | HAO1 (0.44) | LTA4HCA2CA9CA14HAO1 | |
| SCHEMBL166276 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL28636364 | 0.83 | LMNA (0.47) | MAOAMAOBCA2CA9CA14 | |
| Bromide SCHEMBL31124594 | 0.83 | LMNA (0.47) | MAOAMAOBCA2CA9CA14 | |
| SCHEMBL7038781 | 0.81 | HAO1 (0.41) | LTA4HCA2CA9CA14HAO1 | |
| SCHEMBL9049234 | 0.81 | HAO1 (0.43) | MAOAMAOBHAO1ARALDH1A1 | |
| SCHEMBL457634 | 0.80 | MAOA (0.74) | MAOAMAOBLTA4HCA2MMP2 | |
| SCHEMBL9242729 | 0.80 | MAOA (0.74) | MAOAMAOBLTA4HCA2MMP2 | |
| SCHEMBL4552441 | 0.79 | FFAR1 (0.49) | ALDH1A1KDM4EMEN1CYP1A2CYP2D6 | |
| SCHEMBL309042 | 0.79 | LTA4H (0.57) | MAOALTA4HCA2HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998454-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 2003-03-26 | — | — | EP | claimed |