Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 9/20 | 0.44 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573859 | 1.00 | CCR5 (0.44) | CCR5NSD3SLC18A3SIGMAR1RIPK1 | |
| SCHEMBL4610216 | 0.87 | CCR5 (0.40) | CCR5NSD3RIPK1KMT2A | |
| SCHEMBL5573716 | 0.86 | CCR5 (0.38) | CCR5NSD3SLC18A3SIGMAR1RIPK1 | |
| SCHEMBL5573722 | 0.86 | CCR5 (0.38) | CCR5NSD3SLC18A3SIGMAR1RIPK1 | |
| SCHEMBL4598546 | 0.85 | ALDH1A1 (0.41) | CCR5SIGMAR1RIPK1HTR6HPGD | |
| SCHEMBL4552558 | 0.84 | CCR5 (0.47) | CCR5 | |
| SCHEMBL14571163 | 0.83 | RIPK1 (0.43) | CCR5NSD3SLC18A3SIGMAR1RIPK1 | |
| SCHEMBL4610211 | 0.82 | CCR5 (0.37) | CCR5HTR6SMN1; SMN2 | |
| SCHEMBL4596490 | 0.80 | GPR119 (0.49) | CCR5KMT2A | |
| SCHEMBL4596495 | 0.80 | GPR119 (0.49) | CCR5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| US-20070066624-A1 | Chemokine receptor binding compounds | ANORMED, INC. (CA) | 2007-03-22 | — | — | US | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | CCR5, CCR4, CCR1 | CCR5 1/4885NSD3 4084/4885SLC18A3 1545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.