Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 15/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597324 | 0.89 | GPR119 (0.51) | GPR119PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL4724963 | 0.89 | GPR119 (0.51) | GPR119PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL13946626 | 0.87 | GPR119 (0.44) | CCR5GPR119OPRD1OPRK1PRKCG | |
| SCHEMBL4552094 | 0.87 | CCR5 (0.49) | CCR5 | |
| SCHEMBL4552736 | 0.81 | CCR5 (0.69) | CCR5 | |
| SCHEMBL4206068 | 0.81 | CCR5 (0.59) | CCR5 | |
| SCHEMBL4208132 | 0.80 | CCR5 (0.69) | CCR5 | |
| SCHEMBL3409468 | 0.80 | EPHX1 (0.36) | CCR5GPR119PRKCGPRKCBPRKCA | |
| SCHEMBL4552252 | 0.79 | CCR5 (0.71) | CCR5 | |
| SCHEMBL5576017 | 0.79 | GPR119 (0.53) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088860-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008070758-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |