Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251464 | 0.82 | CA12 (0.52) | ALDH1A1KDM4EKMT2AGAAMEN1 | |
| SCHEMBL9249030 | 0.79 | HSP90AB1 (0.59) | ALDH1A1KMT2AGAAMEN1MAPT | |
| SCHEMBL30267852 | 0.77 | HSP90AB1 (0.61) | ALDH1A1KDM4EKMT2AGAAMEN1 | |
| SCHEMBL9325505 | 0.77 | ALDH1A1 (0.57) | ALDH1A1KDM4EKMT2AGAAMEN1 | |
| SCHEMBL459040 | 0.77 | HSP90AB1 (0.61) | ALDH1A1KDM4EKMT2AGAAMEN1 | |
| SCHEMBL4624113 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2AGAAMEN1 | |
| SCHEMBL30342996 | 0.75 | CHRNA7 (0.44) | ALDH1A1KDM4EKMT2AGAAMEN1 | |
| SCHEMBL22995621 | 0.74 | KMT2A (0.45) | ALDH1A1KDM4EKMT2AGAAMEN1 | |
| SCHEMBL7139595 | 0.74 | HSD17B3 (0.52) | ALDH1A1KDM4EKMT2AGAAMEN1 | |
| SCHEMBL17052384 | 0.72 | CYP3A4 (0.34) | KDM4EGAAHPGDTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910269-B1 | METHOD OF SYNTHESIZING KEY INTERMEDIATES FOR THE PRODUCTION OF CAMPTOTHECIN DERIVATIVES | AVRA LAB PVT LTD (IN) | 2013-09-18 | — | — | EP | disclosed |
| US-7608740-B2 | Method of synthesizing key intermediates for the production of camptothecin derivatives | Avra Laboratories Pvt. Ltd (IN) | 2009-10-27 | — | — | US | disclosed |
| US-20080221358-A1 | Method of Synthesizing Key Intermediates for the Production of Camptothecin Derivatives | AVRA LABORATORIES PVT. LTD. (IN) | 2008-09-11 | — | — | US | disclosed |
| EP-1910269-A2 | METHOD OF SYNTHESIZING KEY INTERMEDIATES FOR THE PRODUCTION OF CAMPTOTHECIN DERIVATIVES | Avra Laboratories PVT. Ltd. (IN) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007015259-A2 | METHOD OF SYNTHESIZING KEY INTERMEDIATES FOR THE PRODUCTION OF CAMPTOTHECIN DERIVATIVES | AVRA LABORATORIES PVT. LTD. (IN) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221358-A1 | Method of Synthesizing Key Intermediates for the Production of Camptothecin Derivatives | DHPS, TOP2A, HCCS | ALDH1A1 1104/4885KDM4E 2772/4885KMT2A 3665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.