Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 5/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4650598 | 0.98 | TAAR1 (0.50) | TAAR1SLC6A2SMN1; SMN2HIF1ALOXL2 | |
| SCHEMBL11139644 | 0.92 | TAAR1 (0.45) | TAAR1SLC6A2SMN1; SMN2HIF1ALOXL2 | |
| SCHEMBL3587753 | 0.91 | TAAR1 (0.48) | TAAR1SLC6A2SMN1; SMN2HIF1ALOXL2 | |
| SCHEMBL27780720 | 0.88 | TAAR1 (0.45) | TAAR1SLC6A2SMN1; SMN2HIF1ALOXL2 | |
| SCHEMBL6364468 | 0.87 | KIF11 (0.50) | TAAR1SLC6A2SMN1; SMN2HIF1ALOXL2 | |
| SCHEMBL7491955 | 0.85 | MAOA (0.52) | TAAR1SLC6A2SMN1; SMN2HIF1ALOXL2 | |
| SCHEMBL28744986 | 0.84 | MAOA (0.50) | TAAR1SLC6A2SMN1; SMN2HIF1ALOXL2 | |
| SCHEMBL9182645 | 0.84 | MAOA (0.50) | TAAR1SLC6A2SMN1; SMN2HIF1ALOXL2 | |
| SCHEMBL27295811 | 0.84 | MAOA (0.50) | TAAR1SLC6A2SMN1; SMN2HIF1ALOXL2 | |
| SCHEMBL7497898 | 0.84 | MAOA (0.50) | TAAR1SLC6A2SMN1; SMN2HIF1ALOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117157281-A | Targeted delivery of 1,2,4, 5-tetraoxacompounds and uses thereof | 西湖大学 | 2023-12-01 | — | — | CN | disclosed |
| CN-115043867-A | Hexa-membered cyclic aminosilane external electron donor, preparation method and application thereof | 中国科学院化学研究所 | 2022-09-13 | — | — | CN | disclosed |
| CN-110194724-B | Compound containing diphenylmethane structure and application thereof | 广州同隽医药科技有限公司 | 2021-07-16 | — | — | CN | disclosed |
| EP-2934533-B1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME (US) | 2017-11-15 | — | — | EP | disclosed |
| EP-3164392-A1 | DENTAL COMPOSITION | Dentsply DeTrey GmbH (DE) | 2017-05-10 | — | — | EP | disclosed |
| US-9573961-B2 | Inhibitors of the renal outer medullary potassium channel | MERCK SHARP & DOHME CORP. (US) | 2017-02-21 | — | — | US | disclosed |
| WO-2016001344-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2016-01-07 | — | — | WO | disclosed |
| CN-103459573-B | Balanced dynamic mixtures for controlled release of perfuming aldehydes and ketones | FIRMENICH S.A. (CH) | 2015-11-25 | — | — | CN | disclosed |
| US-20150329557-A1 | Inhibitors of the Renal Outer Medullary Potassium Channel | MERCK SHARP & DOHME CORP. (US) | 2015-11-19 | — | — | US | disclosed |
| EP-2934533-A2 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | Merck Sharp & Dohme Corp. (US) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014099633-A2 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME CORP. (US) | 2014-06-26 | — | — | WO | disclosed |
| EP-2114899-A2 | CONTROLLED RELEASE OF ACTIVE ALDEHYDES AND KETONES FROM EQUILIBRATED DYNAMIC MIXTURES | Firmenich S.A. (CH) | 2009-11-11 | — | — | EP | disclosed |
| CN-100516066-C | Compounds for treating impaired fundic relaxation | JANSSEN PHARMACEUTICA NV (BE) | 2009-07-22 | — | — | CN | disclosed |
| WO-2008093272-A2 | CONTROLLED RELEASE OF ACTIVE ALDEHYDES AND KETONES FROM EQUILIBRATED DYNAMIC MIXTURES | FIRMENICH SA (CH) | 2008-08-07 | — | — | WO | disclosed |
| CN-1288157-C | Dioxinopyridine compounds for the treatment of impaired fundic relaxation, process for their preparation and their use | JANSSEN PHARMACEUTICA NV (BE) | 2006-12-06 | — | — | CN | disclosed |
| CN-1781921-A | Compounds for treating impaired fundic relaxation | JANSSEN PHARMACEUTICA NV (BE) | 2006-06-07 | — | — | CN | disclosed |
| CN-1437602-A | Compounds for treating impaired fundic relaxation | JANSSEN PHARMACEUTICA NV (BE) | 2003-08-20 | — | — | CN | disclosed |
| US-5677350-A | Inhibition of cancer cell growth, proliferation, and metastasis using N,N'-dα,ω-diaminoalkanes | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1997-10-14 | — | — | US | disclosed |
| WO-1996040096-A1 | INHIBITION OF CANCER CELL GROWTH, PROLIFERATION AND METASTASIS USING N,N'-DIBENZYL-α,φ-DIAMINOALKANES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1996-12-19 | — | — | WO | disclosed |
| US-3968298-A | Process for imparting to natural keratin-containing material a permanent finish rendering the material resistant to damage by insects | CIBA-GEIGY CORPORATION (US) | 1976-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329557-A1 | Inhibitors of the Renal Outer Medullary Potassium Channel | KCNJ11, KCNJ1, KCNJ2 | TAAR1 1091/4885SLC6A2 253/4885SMN1; SMN2 1689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.