SCHEMBL6364468

SCHEMBL6364468

NCCCC(N)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 6/20 0.50
TAAR1 Q96RJ0 2/20 0.48
MAOA P21397 1/20 0.48
SLC6A2 P23975 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.44
HIF1A Q16665 1/20 0.44
HTR2A P28223 2/20 0.43
LOXL2 Q9Y4K0 2/20 0.43
CYP2A6 P11509 1/20 0.43
ARG1 P05089 1/20 0.39
ARG2 P78540 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7491955 0.94 MAOA (0.52) KIF11TAAR1MAOASLC6A2SMN1; SMN2
SCHEMBL27295811 0.92 MAOA (0.50) KIF11TAAR1MAOASLC6A2SMN1; SMN2
SCHEMBL7497898 0.92 MAOA (0.50) KIF11TAAR1MAOASLC6A2SMN1; SMN2
SCHEMBL9182645 0.92 MAOA (0.50) KIF11TAAR1MAOASLC6A2SMN1; SMN2
SCHEMBL28744986 0.92 MAOA (0.50) KIF11TAAR1MAOASLC6A2SMN1; SMN2
SCHEMBL3583482 0.89 KIF11 (0.44) KIF11TAAR1MAOASLC6A2SMN1; SMN2
SCHEMBL4552971 0.87 TAAR1 (0.52) KIF11TAAR1MAOASLC6A2SMN1; SMN2
Hydrochloric Acid SCHEMBL4650598 0.85 TAAR1 (0.50) KIF11TAAR1MAOASLC6A2SMN1; SMN2
SCHEMBL29365466 0.84 MAOA (0.43) KIF11TAAR1MAOASLC6A2SMN1; SMN2
SCHEMBL14346444 0.81 KIF11 (0.38) KIF11TAAR1MAOASLC6A2HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0973726-B1 METHOD FOR SYNTHESIS OF RHIZOFERRIN UNIV FLORIDA (US) 2005-04-06 EP claimed
CN-111989316-B Process for the production of (6S, 15S) -3,8,13,18-tetraazaeicosane-6, 15-diol 潘贝拉治疗股份有限公司 2023-09-08 CN disclosed
CN-111989316-A Process for the production of (6S,15S) -3,8,13, 18-tetraazaeicosane-6, 15-diol 太阳生物制药股份有限公司 2020-11-24 CN disclosed
EP-0973726-B1 METHOD FOR SYNTHESIS OF RHIZOFERRIN UNIV FLORIDA (US) 2005-04-06 EP disclosed
EP-1177197-A2 POLYAMINES AND THEIR USE IN THERAPY Slil Biomedical Corporation (US) 2002-02-06 EP disclosed
WO-2000066587-A2 POLYAMINES AND THEIR USE IN THERAPY SLIL BIOMEDICAL CORPORATION (US) 2000-11-09 WO disclosed