SCHEMBL455311

SCHEMBL455311

CCc1cc[c]c(Br)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1636808 0.83 CNR1 (0.39)
SCHEMBL7585287 0.79
SCHEMBL3635076 0.78 PTGS2 (0.41)
SCHEMBL21194021 0.77
SCHEMBL21550330 0.77
SCHEMBL28476733 0.77
SCHEMBL15067982 0.76 TRPA1 (0.39)
SCHEMBL455762 0.74
SCHEMBL311359 0.74 TRPA1 (0.38)
SCHEMBL1100100 0.74 KDM4E (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2903440-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES Bayer CropScience AG (DE) 2015-08-12 EP claimed
WO-2014053450-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2014-04-10 WO claimed
US-6686347-B2 RHEUMATIC DISEASES; ANALGESICS; ENZYME INHIBITORS NOVARTIS AG (CH) 2004-02-03 US claimed
CN-116745289-A Agonists of free fatty acid receptor 1 and their use in diseases associated with said receptor 奥洛治疗有限公司 2023-09-12 CN disclosed
CN-110372614-B Tetrahydroquinoxaline compound, preparation method and application thereof 山东师范大学 2020-09-29 CN disclosed
EP-3045450-B1 INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS SUMITOMO CHEMICAL CO (JP) 2018-02-07 EP disclosed
EP-3045450-A1 INTERMEDIATE COMPOUNDS IN A PROCESS FOR PRODUCING PYRIDAZINONE COMPOUNDS SUMITOMO CHEMICAL CO., LTD. (JP) 2016-07-20 EP disclosed
EP-2614053-B1 METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATES THEREOF SUMITOMO CHEMICAL CO (JP) 2016-03-23 EP disclosed
WO-2015144652-A2 HETEROCYCLIC COMPOUNDS FOR THE CONTROL OF UNWANTED MICROORGANISMS BAYER CROPSCIENCE AG (DE) 2015-10-01 WO disclosed
EP-2903440-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES Bayer CropScience AG (DE) 2015-08-12 EP disclosed
US-9040709-B2 Method for producing pyridazinone compounds and intermediate thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-05-26 US disclosed
EP-0980867-A1 KETONE DERIVATIVES AND MEDICINAL USE THEREOF TORAY INDUSTRIES, INC. (JP) 2000-02-23 EP disclosed
CN-1242770-A Cyclic ketone derivative and pharmaceutical use thereof TORAY INDUSTRIES (JP) 2000-01-26 CN disclosed
EP-0962456-A1 CYCLIC KETONE DERIVATIVE AND PHARMACEUTICAL USE THEREOF TORAY INDUSTRIES, INC. (JP) 1999-12-08 EP disclosed
US-4110332-A PESTICIDES CHEVRON RESEARCH COMPANY (US) 1978-08-29 US disclosed
US-4098896-A FUNGICIDES CHEVRON RESEARCH COMPANY (US) 1978-07-04 US disclosed
US-4034105-A Nematocidal N-cyanoformyl carbamates and N-cyanoformyl thiolcarbamates CHEVRON RESEARCH COMPANY (US) 1977-07-05 US disclosed
US-4003701-A PRINTING A THIOATED FABRIC USING MICROWAVE ENERGY SCOTT PAPER COMPANY (US) 1977-01-18 US disclosed
US-3958000-A Fungicidal 2-arylthio-, 2-alkylthio- and 2-haloalkylthio-1,2,4-oxadiazolidine-3,5-diones CHEVRON RESEARCH COMPANY (US) 1976-05-18 US disclosed
US-3956364-A NAMATOCIDE CHEVRON RESEARCH COMPANY (US) 1976-05-11 US disclosed