Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.60 |
| ▸ | ASIC3 | Q9UHC3 | 5/20 | 0.53 |
| ▸ | PNMT | P11086 | 2/20 | 0.50 |
| ▸ | CD44 | P16070 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.43 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.43 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.43 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.43 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.43 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.43 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.43 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.43 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3704728 | 0.80 | CD274 (0.55) | CD274ASIC3PNMTCD44MAOB | |
| SCHEMBL25402840 | 0.79 | CD274 (0.61) | CD274ASIC3PNMTCD44MAOB | |
| SCHEMBL3703063 | 0.79 | CD274 (0.54) | CD274ASIC3PNMTCD44MAOB | |
| SCHEMBL6347388 | 0.78 | ASIC3 (0.65) | CD274ASIC3PNMTCD44MAOB | |
| SCHEMBL27977079 | 0.78 | ESR2 (0.49) | DRD2DRD3DRD1ADCY8ADCY1 | |
| SCHEMBL27663193 | 0.78 | ESR2 (0.49) | DRD2DRD3DRD1 | |
| SCHEMBL22866959 | 0.78 | CD274 (0.86) | CD274ASIC3PNMTCD44MAOB | |
| SCHEMBL24842524 | 0.78 | CD274 (0.60) | CD274ASIC3PNMTCD44MAOB | |
| SCHEMBL25405965 | 0.78 | CD274 (0.74) | CD274ASIC3PNMTCD44MAOB | |
| SCHEMBL30534720 | 0.78 | CD274 (0.60) | CD274ASIC3PNMTCD44MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021213358-A1 | BORON-CONTAINING COMPOUNDS AND APPLICATION THEREOF | 江苏先声药业有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |
| EP-2114890-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008097428-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2008-08-14 | — | — | WO | disclosed |