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SCHEMBL455334

SCHEMBL455334

CC(C)(C)c1ccc(-c2c3c(c(-c4ccc(C(C)(C)C)cc4C(C)(C)C)c(-c4ccc(C(C)(C)C)cc4C(C)(C)C)c2-c2ccc(C(C)(C)C)cc2C(C)(C)C)-c2ccccc2-3)c(C(C)(C)C)c1.O=[PH](O)O[PH](=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 3/20 0.44
▸ RAB9A P51151 3/20 0.44
▸ CASP3 P42574 2/20 0.44
▸ SENP8 Q96LD8 2/20 0.44
▸ SENP7 Q9BQF6 2/20 0.44
▸ SENP6 Q9GZR1 2/20 0.44
▸ ALDH1A1 P00352 2/20 0.44
▸ L3MBTL1 Q9Y468 2/20 0.44
▸ PLA2G1B P04054 1/20 0.44
▸ NFKB1 P19838 1/20 0.44
▸ NFKB2 Q00653 1/20 0.44
▸ RELA Q04206 1/20 0.44
▸ ATG4B Q9Y4P1 1/20 0.44
▸ NR1H3 Q13133 1/20 0.35
▸ LMNA P02545 2/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ ATM Q13315 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ APEX1 P27695 1/20 0.34
▸ MAPT P10636 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31658325 1.00 NPC1 (0.44) NPC1RAB9ACASP3SENP8SENP7
Phosphonic Acid SCHEMBL455332 0.91 ALDH1A1 (0.49) NPC1RAB9ACASP3SENP8SENP7
Phosphonic Acid SCHEMBL9417604 0.87 ALDH1A1 (0.45) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL202531 0.86 NPC1 (0.35) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL228138 0.84 ALDH1A1 (0.53) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL28783172 0.83 RXRA (0.40) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL28891736 0.83 RXRA (0.40) NPC1RAB9ACASP3SENP8SENP7
Phosphonic Acid SCHEMBL2197000 0.82 ALDH1A1 (0.51) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL30285371 0.81 ALDH1A1 (0.44) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL6027001 0.79 ALDH1A1 (0.42) NPC1RAB9ACASP3SENP8SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5342869-A Monophosphonate, diphosphonate, phosphonate-phosphonite stabilizers against weathering SANDOZ LTD. (CH) 1994-08-30 — — US claimed
CN-117801648-A Aqueous resin coating composition, heat ray shielding film using same, and method for producing same 株式会社ADEKA 2024-04-02 — — CN disclosed
CN-105820763-B Optical adhesive sheet 日东电工株式会社 2021-10-26 — — CN disclosed
CN-112334503-A Curable compositions based on multistage polymers 阿科玛法国公司 2021-02-05 — — CN disclosed
CN-111712539-A Nucleating agent, polyolefin resin composition using same, and molded article thereof 株式会社ADEKA 2020-09-25 — — CN disclosed
EP-1795560-B1 POLYLACTIC ACID RESIN COMPOSITION, MOLDINGS, AND PROCESS FOR PRODUCTION THEREOF ADEKA CORP (JP) 2013-05-22 — — EP disclosed
US-20120065306-A1 LONG-FIBER REINFORCED RESIN COMPOSITION AND MOLDED OBJECT THEREOF PRIME POLYMER CO., LTD. (JP) 2012-03-15 — — US disclosed
US-7910643-B2 Polylactic acid resin composition, moldings, and process for production thereof ADEKA CORPORATION (JP) 2011-03-22 — — US disclosed
US-20100174017-A1 Polylactic Acid Resin Composition, Moldings, and Process for Production Thereof ADEKA CORPORATION (JP) 2010-07-08 — — US disclosed
EP-1795560-A1 POLYLACTIC ACID RESIN COMPOSITION, MOLDINGS, AND PROCESS FOR PRODUCTION THEREOF Adeka Corporation (JP) 2007-06-13 — — EP disclosed
US-20050106348-A1 Wire-protective tube YAZAKI CORPORATION 2005-05-19 — — US disclosed
US-6852921-B1 Wire-protective tube YAZAKI CORPORATION (JP) 2005-02-08 — — US disclosed
US-5342869-A Monophosphonate, diphosphonate, phosphonate-phosphonite stabilizers against weathering SANDOZ LTD. (CH) 1994-08-30 — — US disclosed