SCHEMBL4553369

SCHEMBL4553369

C=CNCCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
TAAR1 Q96RJ0 2/20 0.52
ALDH1A1 P00352 2/20 0.52
ATM Q13315 1/20 0.52
KDM1A O60341 1/20 0.52
LMNA P02545 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
HTR1A P08908 1/20 0.52
ADRA2A P08913 1/20 0.52
CYP2C8 P10632 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C9 P11712 1/20 0.52
IDO1 P14902 1/20 0.52
TSHR P16473 1/20 0.52
NFKB1 P19838 1/20 0.52
MAOA P21397 1/20 0.52
PTGS1 P23219 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9344083 0.98 L3MBTL1 (0.52) NPC1RAB9ASMN1; SMN2TAAR1ALDH1A1
SCHEMBL19711877 0.87 SIGMAR1 (0.59) KCNH2SIGMAR1L3MBTL1
Hydrochloric Acid SCHEMBL2493107 0.85 SIGMAR1 (0.57) KCNH2SIGMAR1L3MBTL1
SCHEMBL21130504 0.85 SIGMAR1 (0.63) KCNH2SIGMAR1
SCHEMBL9191244 0.84 SIGMAR1 (0.62) SIGMAR1L3MBTL1
SCHEMBL9602490 0.84 SIGMAR1 (0.62) SIGMAR1L3MBTL1
SCHEMBL15943387 0.81 MEN1 (0.68) SMN1; SMN2ALDH1A1MAOASIGMAR1GAA
SCHEMBL21337811 0.78 L3MBTL1 (0.46) SMN1; SMN2TAAR1ATMLMNACYP2C9
SCHEMBL17385073 0.78 TMEM97 (0.55) SMN1; SMN2TAAR1ALDH1A1LMNAHTR1A
SCHEMBL7736614 0.77 ALDH1A1 (0.52) NPC1RAB9ASMN1; SMN2TAAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210283273-A1 NON-VIRAL DELIVERY AGENTS FROM POLYELECTROLYTES BASED ON CYCLOPROPENIUM IONS, THEIR SYNTHESES, AND USES THEREOF NATIONAL SCIENCE FOUNDATION 2021-09-16 US claimed
WO-2018035435-A1 NON-VIRAL DELIVERY AGENTS FROM POLYELECTROLYTES BASED ON CYCLOPROPENIUM IONS, THEIR SYNTHESES, AND USES THEREOF THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2018-02-22 WO claimed
EP-1633471-B1 PERCARBOXYLIC ACID-BASED POLYELECTROLYTE CAPSULE SYSTEM HAVING A LONG SHELF LIFE HENKEL AG & CO KGAA (DE) 2009-03-25 EP claimed
EP-0284081-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1994-08-10 EP claimed
JP-62041234-A None JP disclosed
JP-62041235-A None JP disclosed
CN-115243780-A Filter material 东丽株式会社 2022-10-25 CN disclosed
EP-3257583-B1 CHARGE REVERSIBLE ION EXCHANGE RESINS, CHROMATOGRAPHY COLUMN, METHOD, AND SYSTEM THEREOF DIONEX CORP (US) 2021-09-22 EP disclosed
US-20210283273-A1 NON-VIRAL DELIVERY AGENTS FROM POLYELECTROLYTES BASED ON CYCLOPROPENIUM IONS, THEIR SYNTHESES, AND USES THEREOF NATIONAL SCIENCE FOUNDATION 2021-09-16 US disclosed
CN-111621863-A Processing technology of functional nano regenerated fiber 苏州新民丝绸有限公司 2020-09-04 CN disclosed
CN-107522809-B Charge-reversible ion exchange resins, chromatography columns, methods, and systems thereof 戴安公司 2020-04-10 CN disclosed
US-10379090-B2 Charge reversible ion exchange resins, chromatography column, method, and system thereof DIONEX CORPORATION (US) 2019-08-13 US disclosed
EP-0715638-A1 SILICONE GRAFTED THERMOPLASTIC ELASTOMERIC COPOLYMERS AND HAIR AND SKIN CARE COMPOSITIONS CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 1996-06-12 EP disclosed
EP-0706536-A1 THERMOPLASTIC ELASTOMERIC COPOLYMERS AND HAIR AND SKIN CARE, COMPOSITIONS CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 1996-04-17 EP disclosed
US-5412066-A Adhesives THER UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1995-05-02 US disclosed
US-5407581-A Filter medium having a limited surface negative charge for treating a blood material ASAHI MEDICAL CO., LTD. (JP) 1995-04-18 US disclosed
WO-1995006078-A1 SILICONE GRAFTED THERMOPLASTIC ELASTOMERIC COPOLYMERS AND HAIR AND SKIN CARE COMPOSITIONS CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 1995-03-02 WO disclosed
WO-1995001383-A1 THERMOPLASTIC ELASTOMERIC COPOLYMERS AND HAIR AND SKIN CARE, COMPOSITIONS CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 1995-01-12 WO disclosed
JP-S6241235-A NOVEL ANION EXCHANGE MEMBRANE ASAHI CHEM IND CO LTD 1987-02-23 JP disclosed
JP-S6241234-A IMPROVE ANION-EXCHANGE MEMBRANE ASAHI CHEM IND CO LTD 1987-02-23 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210283273-A1 NON-VIRAL DELIVERY AGENTS FROM POLYELECTROLYTES BASED ON CYCLOPROPENIUM IONS, THEIR SYNTHESES, AND USES THEREOF PARG, TET1, PUF60 NPC1 2000/4885RAB9A 4664/4885SMN1; SMN2 2422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.