Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | LTK | P29376 | 1/20 | 0.41 |
| ▸ | GRK5 | P34947 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29414648 | 0.85 | MAP4K4 (0.49) | CHEK1MAP4K4ABL1NTRK1LCK | |
| SCHEMBL28465298 | 0.85 | MAP4K4 (0.49) | CHEK1MAP4K4ABL1NTRK1LCK | |
| SCHEMBL1263501 | 0.83 | ADORA2A (0.39) | CHEK1KDRFLT3RAB9AADORA1 | |
| SCHEMBL7164278 | 0.82 | ALDH1A1 (0.42) | CHEK1MAP4K4ABL1NTRK1LCK | |
| SCHEMBL1838861 | 0.80 | ALDH1A1 (0.50) | MAP4K4CSF1RPIM1FGFR1PDGFRA | |
| SCHEMBL11629135 | 0.80 | RAB9A (0.50) | CHEK1MAP4K4ABL1NTRK1LCK | |
| Ammonia Solution, Strong SCHEMBL29089079 | 0.78 | RAB9A (0.49) | CHEK1MAP4K4ABL1NTRK1LCK | |
| SCHEMBL4553382 | 0.76 | RAB9A (0.50) | CHEK1MAP4K4ABL1NTRK1LCK | |
| SCHEMBL8397637 | 0.76 | CD44 (0.42) | CHEK1CDK8ACVR1RAB9AADORA1 | |
| SCHEMBL397078 | 0.76 | ALDH1A1 (0.58) | CHEK1MAP4K4ABL1NTRK1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622231-B2 | Imaging members containing intermixed polymer charge transport component layer | XEROX CORPORATION (US) | 2009-11-24 | — | — | US | disclosed |
| US-20080057426-A1 | Photoconductors | XEROX CORPORATION | 2008-03-06 | — | — | US | disclosed |