Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | LTA4H | P09960 | 7/20 | 0.57 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | BAX | Q07812 | 1/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508788 | 0.88 | ST14 (0.48) | ESR1ESR2MEN1KMT2ALTA4H | |
| SCHEMBL1660264 | 0.85 | — | — | |
| SCHEMBL27605661 | 0.83 | ESR1 (0.55) | ESR1ESR2MEN1KMT2ALTA4H | |
| SCHEMBL27511812 | 0.83 | ESR1 (0.55) | ESR1ESR2MEN1KMT2ALTA4H | |
| SCHEMBL12804316 | 0.81 | ESR1 (0.70) | ESR1ESR2MEN1KMT2ALTA4H | |
| SCHEMBL5488305 | 0.81 | ESR1 (0.70) | ESR1ESR2MEN1KMT2ALTA4H | |
| SCHEMBL12804905 | 0.81 | ESR1 (0.70) | ESR1ESR2MEN1KMT2ALTA4H | |
| SCHEMBL14421265 | 0.81 | ESR1 (0.70) | ESR1ESR2MEN1KMT2ALTA4H | |
| SCHEMBL18198 | 0.80 | ESR2 (1.00) | ESR1ESR2MEN1KMT2ALTA4H | |
| SCHEMBL249169 | 0.80 | ESR2 (1.00) | ESR1ESR2MEN1KMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6989052-B1 | Phase change ink printing process | XEROX CORPORATION (US) | 2006-01-24 | — | — | US | claimed |
| EP-2137193-A2 | SUBSTITUTED DIHYDRO AND TETRAHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | Sanofi-Aventis (FR) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008112483-A2 | SUBSTITUTED DIHYDRO AND TETRAHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | SANOFI-AVENTIS (FR) | 2008-09-18 | — | — | WO | disclosed |