SCHEMBL12804316

SCHEMBL12804316

Oc1ccc(Oc2ccc(CCc3ccc(Oc4ccc(O)cc4)cc3)cc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 2/20 0.70
▸ ESR2 Q92731 2/20 0.70
▸ KMT2A Q03164 2/20 0.70
▸ MEN1 O00255 1/20 0.70
▸ LTA4H P09960 7/20 0.58
▸ NR1H2 P55055 1/20 0.58
▸ BAX Q07812 1/20 0.58
▸ CALM1 P0DP23 1/20 0.57
▸ CA2 P00918 1/20 0.54
▸ KDM4E B2RXH2 1/20 0.52
▸ ALDH1A1 P00352 1/20 0.52
▸ HTR1A P08908 1/20 0.52
▸ ADRA2A P08913 1/20 0.52
▸ SLC6A2 P23975 1/20 0.52
▸ CYP2C19 P33261 1/20 0.52
▸ HTR3A P46098 1/20 0.52
▸ BACE1 P56817 1/20 0.52
▸ TAAR1 Q96RJ0 1/20 0.52
▸ L3MBTL1 Q9Y468 1/20 0.52
▸ BLM P54132 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6062245 0.91 LTA4H (0.68) ESR1ESR2KMT2AMEN1LTA4H
SCHEMBL20672211 0.87 ESR1 (0.58) ESR1ESR2KMT2AMEN1LTA4H
SCHEMBL1837915 0.87 LTA4H (0.60) ESR1ESR2KMT2AMEN1LTA4H
Thyronamine SCHEMBL449823 0.87 TAAR1 (0.75) ESR1ESR2KMT2AMEN1LTA4H
SCHEMBL12804905 0.85 ESR1 (0.70) ESR1ESR2KMT2AMEN1LTA4H
SCHEMBL5488305 0.85 ESR1 (0.70) ESR1ESR2KMT2AMEN1LTA4H
SCHEMBL14421265 0.85 ESR1 (0.70) ESR1ESR2KMT2AMEN1LTA4H
SCHEMBL249169 0.84 ESR2 (1.00) ESR1ESR2KMT2AMEN1LTA4H
SCHEMBL7811939 0.84 ESR2 (1.00) ESR1ESR2KMT2AMEN1LTA4H
SCHEMBL3175106 0.84 ESR2 (1.00) ESR1ESR2KMT2AMEN1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760738-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor United States of America as represented by the Adminstrator of NASA (US) 2023-09-19 — — US disclosed
US-20220017479-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA 2022-01-20 — — US disclosed
US-11130742-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) 2021-09-28 — — US disclosed
US-20200247770-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA 2020-08-06 — — US disclosed
US-10626098-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly (imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) 2020-04-21 — — US disclosed
US-20180118702-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR UNITES STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA 2018-05-03 — — US disclosed
US-9822088-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) 2017-11-21 — — US disclosed
US-20120252968-A1 Anisotropic Copoly(imide Oxetane) Coatings and Articles of Manufacture, Copoly(imide Oxetane)s Containing Pendant Fluorocarbon Moieties, Oligomers and Processes Therefor U.S.A. AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2012-10-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120252968-A1 Anisotropic Copoly(imide Oxetane) Coatings and Articles of Manufacture, Copoly(imide Oxetane)s Containing Pendant Fluorocarbon Moieties, Oligomers and Processes Therefor MACF1, OR51E2, EZR ESR1 2319/4885ESR2 4421/4885KMT2A 4018/4885
US-20180118702-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR MACF1, OR51E2, FOS ESR1 2404/4885ESR2 4464/4885KMT2A 4021/4885
US-11760738-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor MACF1, OR51E2, FOS ESR1 2404/4885ESR2 4464/4885KMT2A 4021/4885
US-20200247770-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR MACF1, OR51E2, FOS ESR1 2404/4885ESR2 4464/4885KMT2A 4021/4885
US-10626098-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly (imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor MACF1, OR51E2, FOS ESR1 2404/4885ESR2 4464/4885KMT2A 4021/4885
US-11130742-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor MACF1, OR51E2, FOS ESR1 2404/4885ESR2 4464/4885KMT2A 4021/4885
US-20220017479-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR MACF1, OR51E2, FOS ESR1 2404/4885ESR2 4464/4885KMT2A 4021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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