Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 2/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4360505 | 0.75 | DHODH (0.47) | FABP4DHODHFABP3PRNPPPARG | |
| SCHEMBL4553637 | 0.71 | TBK1 (0.43) | HTR2CFABP4FABP5GABRA1GABRB2 | |
| SCHEMBL4362424 | 0.70 | ELANE (0.44) | FABP4FABP5DHODHFABP3 | |
| SCHEMBL17323546 | 0.67 | HTR2C (0.51) | HTR2CHTR6GABRA1GABRB2 | |
| SCHEMBL13646083 | 0.66 | HTR2C (0.61) | HTR2CHTR6 | |
| SCHEMBL27584180 | 0.65 | HTR2C (0.49) | HTR2CGABRA1GABRB2 | |
| SCHEMBL11012434 | 0.65 | KDM4E (0.51) | FABP4DHODHFABP3PRNPPPARG | |
| SCHEMBL2152544 | 0.64 | HTR6 (0.47) | HTR2CHTR6GABRA1GABRB2 | |
| SCHEMBL743113 | 0.64 | ALDH1A1 (0.47) | — | |
| SCHEMBL620681 | 0.63 | HSD17B10 (0.46) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270450-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270450-A1 | CHEMICAL COMPOUNDS | CSF1R, CSF3R, FLT3 | HTR2C 4446/4885HTR6 4502/4885FABP4 1756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.