Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3759516 | 0.79 | — | — | |
| SCHEMBL4554514 | 0.79 | TSHR (0.35) | S1PR1NR3C1KDM4ECTSKPOLB | |
| SCHEMBL5376044 | 0.72 | — | — | |
| SCHEMBL30565846 | 0.69 | KDM4E (0.43) | S1PR1KDM4EPOLBCYP1A2 | |
| SCHEMBL4555331 | 0.68 | KDM4E (0.35) | KDM4EPOLBCYP1A2 | |
| SCHEMBL4439919 | 0.67 | KDM4E (0.36) | KDM4EPOLBCYP1A2CYP2D6 | |
| SCHEMBL11212520 | 0.67 | NFE2L2 (0.46) | KDM4EPOLB | |
| SCHEMBL4570114 | 0.67 | ALDH1A1 (0.33) | — | |
| SCHEMBL4555941 | 0.66 | ALOX5AP (0.31) | — | |
| SCHEMBL11209129 | 0.65 | KDM4E (0.44) | KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120939-A2 | SUBSTITUTED PYRIDINE N-OXIDE HERBICIDES | E. I. Du Pont de Nemours and Company (US) | 2009-11-25 | — | — | EP | claimed |
| WO-2008100426-A2 | SUBSTITUTED PYRIDINE N-OXIDE HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-08-21 | — | — | WO | claimed |