Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOS | P01100 | 2/20 | 0.61 |
| ▸ | JUN | P05412 | 2/20 | 0.61 |
| ▸ | GSK3B | P49841 | 6/20 | 0.60 |
| ▸ | BACE1 | P56817 | 6/20 | 0.60 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.55 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.49 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4554033 | 1.00 | FOS (0.61) | FOSJUNGSK3BBACE1NFE2L2 | |
| SCHEMBL4554034 | 1.00 | FOS (0.61) | FOSJUNGSK3BBACE1NFE2L2 | |
| SCHEMBL5598783 | 0.88 | NFE2L2 (0.65) | NFE2L2MMP1MMP2MMP9MAOA | |
| SCHEMBL5598785 | 0.88 | NFE2L2 (0.65) | NFE2L2MMP1MMP2MMP9MAOA | |
| SCHEMBL79651 | 0.82 | NFE2L2 (0.63) | BACE1NFE2L2MMP1MMP2MMP9 | |
| SCHEMBL7654865 | 0.82 | NFE2L2 (0.63) | BACE1NFE2L2MMP1MMP2MMP9 | |
| SCHEMBL79650 | 0.82 | NFE2L2 (0.63) | BACE1NFE2L2MMP1MMP2MMP9 | |
| SCHEMBL30337035 | 0.82 | NFE2L2 (0.63) | BACE1NFE2L2MMP1MMP2MMP9 | |
| SCHEMBL609310 | 0.81 | FOS (0.68) | FOSJUNGSK3BBACE1TLR9 | |
| SCHEMBL609311 | 0.81 | FOS (0.68) | FOSJUNGSK3BBACE1TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090263492-A1 | Diagnostic Methods and Genetic Markers for Alzheimer Disease | HUMAN BIOMOLECULAR RESEARCH INSTITUTE | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090263492-A1 | Diagnostic Methods and Genetic Markers for Alzheimer Disease | CHAT, SLC18A3, GAP43 | FOS 4099/4885JUN 4432/4885GSK3B 2770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.