Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28096697 | 0.89 | HSD11B1 (0.45) | SMN1; SMN2HPGDRAB9ALMNAHTT | |
| Bromide SCHEMBL28400140 | 0.86 | RARB (0.48) | MAPTHTTRARB | |
| SCHEMBL29068251 | 0.84 | SMN1; SMN2 (0.42) | MAPTSMN1; SMN2HPGDRAB9AKDM4E | |
| SCHEMBL23403331 | 0.83 | CYP1A2 (0.39) | MAPTSMN1; SMN2HPGDRAB9AKDM4E | |
| SCHEMBL28347037 | 0.82 | RARB (0.48) | MAPTHPGDHTTRARBGAA | |
| SCHEMBL456713 | 0.81 | ESR2 (0.50) | MAPTSMN1; SMN2HPGDRAB9AKDM4E | |
| SCHEMBL455218 | 0.81 | DCLRE1A (0.42) | MAPTSMN1; SMN2HPGDRAB9AKDM4E | |
| SCHEMBL5595171 | 0.81 | SMN1; SMN2 (0.40) | MAPTSMN1; SMN2HPGDRAB9AKDM4E | |
| SCHEMBL23399403 | 0.80 | LMNA (0.37) | MAPTSMN1; SMN2HPGDRAB9AKDM4E | |
| SCHEMBL24540416 | 0.79 | ALDH1A1 (0.63) | MAPTSMN1; SMN2HPGDRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614053-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |