Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | AXL | P30530 | 2/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | STK10 | O94804 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | CDK11B | P21127 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | BLK | P51451 | 1/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3198213 | 0.81 | HTT (0.42) | KMT2AMEN1ACHEBCHELMNA | |
| SCHEMBL13486187 | 0.76 | ALDH1A1 (0.52) | KMT2AMEN1AURKAAXLDDR1 | |
| SCHEMBL3209155 | 0.76 | ALDH1A1 (0.43) | KMT2AAURKAAXLDDR1AURKB | |
| SCHEMBL3200212 | 0.75 | ALDH1A1 (0.42) | KMT2AAURKAAXLDDR1AURKB | |
| SCHEMBL3211788 | 0.74 | KMT2A (0.51) | KMT2AMEN1ATMLMNAHTT | |
| SCHEMBL3198331 | 0.73 | HTT (0.45) | KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL3209730 | 0.73 | LMNA (0.49) | KMT2AACHELMNAHTTSMN1; SMN2 | |
| SCHEMBL3198917 | 0.72 | CALM1 (0.45) | ATMLDHA | |
| SCHEMBL3214638 | 0.72 | MAPK1 (0.53) | KMT2ALMNAHTTSMN1; SMN2LDHA | |
| SCHEMBL27936118 | 0.72 | SMN1; SMN2 (0.54) | KMT2AMEN1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010495-A2 | NEW HYDROXYPHENYL DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF | Mutabilis SA (FR) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007135562-A2 | HYDROXYPHENYL DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF | MUTABILIS S.A. (FR) | 2007-11-29 | — | — | WO | disclosed |