SCHEMBL4555933

SCHEMBL4555933

C=CC[Si](CC=C)(CC=C)NC(C)=O

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
KDM4E B2RXH2 1/20 0.30
CA2 P00918 1/20 0.30
PTGS1 P23219 1/20 0.30
MMP12 P39900 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6697493 0.82 ALDH1A1 (0.30) ALDH1A1
SCHEMBL8154998 0.80 LMNA (0.30)
SCHEMBL7650037 0.72 MEN1 (0.38) ALDH1A1KDM4E
SCHEMBL8526595 0.72
SCHEMBL6606095 0.70 KDM4E (0.35) ALDH1A1KDM4ECA2PTGS1MMP12
SCHEMBL14760129 0.69 ALDH1A1 (0.38) ALDH1A1
SCHEMBL244477 0.68
SCHEMBL25175178 0.67
SCHEMBL10874824 0.67 PAOX (0.37) ALDH1A1KDM4ECA2PTGS1MMP12
SCHEMBL450522 0.66 KDM4E (0.41) ALDH1A1KDM4ECA2PTGS1MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200156291-A1 ANISOTROPIC FILM AND METHOD FOR MANUFACTURING ANISOTROPIC FILM SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-05-21 US disclosed
US-9653307-B1 Surface modification compositions, methods of modifying silicon-based materials, and methods of forming high aspect ratio structures MICRON TECHNOLOGY, INC. (US) 2017-05-16 US disclosed
EP-1780242-B1 Resin composition for sealing optical device and method of sealing semiconductor element SHINETSU CHEMICAL CO (JP) 2013-10-09 EP disclosed
US-20130200425-A1 PHOSPHOR-CONTAINING ADHESIVE SILICONE COMPOSITION SHEET, AND METHOD OF PRODUCING LIGHT-EMITTING DEVICE USING SAME SHIN-ETSU CHEMICAL CO., LTD (JP) 2013-08-08 US disclosed
EP-2623576-A1 Adhesive silicone composition sheet containing phosphorus and method of producing light emitting device using the same Shin-Etsu Chemical Co., Ltd. (JP) 2013-08-07 EP disclosed
US-7550204-B2 Resin composition for sealing optical device, cured product thereof, and method of sealing semiconductor element SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-06-23 US disclosed
US-20070099009-A1 a silylated organopolysiloxane and a condensation catalyst; curing to seal; heat resistance and ultraviolet light resistance, excellent optical transparency and favorable toughness SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-05-03 US disclosed
EP-1780242-A2 Resin composition for sealing optical device and method of sealing semiconductor element Shin-Etsu Chemical Co., Ltd. (JP) 2007-05-02 EP disclosed
US-6001856-A β-adrenergic agonists to reduce a wasting condition PFIZER INC. (US) 1999-12-14 US disclosed
US-5977124-A β-adrenergic agonists PFIZER INC. (US) 1999-11-02 US disclosed
US-5907019-A Polymer-compatible polymethylsilsesquioxane DOW CORNING ASIA, LTD. (JP) 1999-05-25 US disclosed
EP-0887079-A1 Beta-Adrenergic agonists to reduce a wasting condition PFIZER INC. (US) 1998-12-30 EP disclosed
EP-0828712-A1 BETA-ADRENERGIC AGONISTS PFIZER INC. (US) 1998-03-18 EP disclosed
EP-0824519-A1 BETA-ADRENERGIC AGONISTS PFIZER INC. (US) 1998-02-25 EP disclosed
WO-1996035671-A1 β-ADRENERGIC AGONISTS PFIZER INC. (US) 1996-11-14 WO disclosed
WO-1996035670-A1 β-ADRENERGIC AGONISTS PFIZER INC. (US) 1996-11-14 WO disclosed
US-4873339-A Chiral biotin precursors LONZA LTD. (CH) 1989-10-10 US disclosed
US-4851540-A Process for the production of biotin precursors LONZA LTD. (CH) 1989-07-25 US disclosed
EP-0299634-A2 Silicone polymer termination DOW CORNING CORPORATION (US) 1989-01-18 EP disclosed