SCHEMBL6606095

SCHEMBL6606095

CC[Si](CC)(CC)NC(C)=O

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
CA2 P00918 1/20 0.35
PTGS1 P23219 1/20 0.35
MMP12 P39900 1/20 0.35
NFKB1 P19838 1/20 0.33
MAPK1 P28482 1/20 0.32
HIF1A Q16665 1/20 0.32
PAOX Q6QHF9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7760312 0.79 CTSD (0.32) ALDH1A1TDP1
SCHEMBL10874824 0.78 PAOX (0.37) KDM4EALDH1A1TDP1CA2PTGS1
SCHEMBL8589436 0.74 LMNA (0.33) CA2NFKB1
SCHEMBL11542665 0.74 PAOX (0.39) KDM4EALDH1A1MAPK1HIF1APAOX
SCHEMBL1953277 0.72 EPHX1 (0.37) ALDH1A1TDP1
SCHEMBL450522 0.71 KDM4E (0.41) KDM4EALDH1A1TDP1CA2PTGS1
SCHEMBL4555933 0.70 ALDH1A1 (0.35) KDM4EALDH1A1CA2PTGS1MMP12
SCHEMBL26965406 0.67 KDM4E (0.44) KDM4EALDH1A1TDP1CA2PTGS1
SCHEMBL2987964 0.67 KDM4E (0.44) KDM4EALDH1A1TDP1CA2PTGS1
SCHEMBL15123076 0.67 ALDH1A1 (0.38) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102432862-A Modified alkoxylation products having at least one non-terminal alkoxysilyl group, with increased storage life and increased stretchability of the polymers prepared using them EVONIK GOLDSCHMIDT GMBH 2012-05-02 CN claimed
US-6703497-B1 SURFACE MODIFIED BY HAVING HYDROXYL FUNCTIONAL GROUPS PRESENT AT THE SURFACE ETHERIFIED BY ORGANIC COMPOUND COMPRISING SILYLATING AGENT, ISOCYANATE, HALOGENATED ALKYLATING AGENT, ALKYLENE OXIDE, OR GLYCIDYL COMPOUND RHODIA CHIMIE (FR) 2004-03-09 US claimed
US-20250091263-A1 Low-Pore Pellets and Methods for Producing Molded Body ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-03-20 US disclosed
US-12186947-B2 Low-pore pellets and method for producing molded body ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-01-07 US disclosed
US-12180344-B2 Cellulose nanofiber-containing aqueous dispersion ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-12-31 US disclosed
US-20240328481-A1 Cellulose-containing Gear ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-10-03 US disclosed
EP-3786215-B1 CELLULOSE NANOFIBER-CONTAINING AQUEOUS DISPERSION AND CELLULOSE NANOFIBER-CONTAINING RESIN COMPOSITION ASAHI CHEMICAL IND (JP) 2024-09-25 EP disclosed
US-20240270948-A1 RESIN COMPOSITION MITSUI CHEMICALS, INC. (JP) 2024-08-15 US disclosed
US-20240240027-A1 METHOD FOR PRODUCING MODIFICATION INORGANIC NANOSHEET, AND MODIFICATION INORGANIC NANOSHEET FUKUOKA INSTITUTE OF TECHNOLOGY (JP) 2024-07-18 US disclosed
US-12007001-B2 Cellulose-containing gear ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-06-11 US disclosed
EP-4040018-B1 A MOLDED ARTICLE ASAHI CHEMICAL IND (JP) 2024-05-22 EP disclosed
US-20120296076-A1 PROCESSES AND INTERMEDIATES FOR PREPARING ANTI-HIV AGENTS GILEAD SCIENCES, INC. 2012-11-22 US disclosed
CN-102432862-A Modified alkoxylation products having at least one non-terminal alkoxysilyl group, with increased storage life and increased stretchability of the polymers prepared using them EVONIK GOLDSCHMIDT GMBH 2012-05-02 CN disclosed
EP-1480943-A2 SYNTHESIS OF 3,5-DIHYDROXY-7-PYRROL-1-YL HEPTANOIC ACIDS Teva Pharmaceutical Industries Limited (IL) 2004-12-01 EP disclosed
WO-2004046105-A2 SYNTHESIS OF 3,5-DIHYDROXY-7-PYRROL-1-YL HEPTANOIC ACIDS TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2004-06-03 WO disclosed
US-6703497-B1 SURFACE MODIFIED BY HAVING HYDROXYL FUNCTIONAL GROUPS PRESENT AT THE SURFACE ETHERIFIED BY ORGANIC COMPOUND COMPRISING SILYLATING AGENT, ISOCYANATE, HALOGENATED ALKYLATING AGENT, ALKYLENE OXIDE, OR GLYCIDYL COMPOUND RHODIA CHIMIE (FR) 2004-03-09 US disclosed
EP-0200141-A2 Photoresist composition NIPPON ZEON CO., LTD. (JP) 1986-11-05 EP disclosed
EP-0031962-B1 FUNGICIDAL AZOLYL-SILYL-GLYCOL ETHERS, THEIR PREPARATION, THEIR USE TO COMBAT FUNGI AND COMPOSITION THEREFOR BASF Aktiengesellschaft (DE) 1983-02-09 EP disclosed
US-4330535-A Fungicidal azolyl-silyl-glycol ethers, their use for combating fungi, and agents therefor BASF AKTIENGESELLSCHAFT (DE) 1982-05-18 US disclosed
EP-0031962-A2 Fungicidal azolyl-silyl-glycol ethers, their preparation, their use to combat fungi and composition therefor BASF Aktiengesellschaft (DE) 1981-07-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120296076-A1 PROCESSES AND INTERMEDIATES FOR PREPARING ANTI-HIV AGENTS SAMHD1, DHPS, LSS KDM4E 1951/4885ALDH1A1 2236/4885TDP1 1786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.