Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.64 |
| ▸ | PGR | P06401 | 9/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.64 |
| ▸ | NR3C2 | P08235 | 12/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4556027 | 0.90 | NR3C1 (0.54) | NR3C1PGRCYP3A4NR3C2 | |
| SCHEMBL6669693 | 0.86 | NR3C1 (0.64) | NR3C1PGRCYP3A4NR3C2 | |
| SCHEMBL3685155 | 0.86 | NR3C1 (0.63) | NR3C1PGRCYP3A4NR3C2 | |
| SCHEMBL676416 | 0.81 | NR3C1 (0.64) | NR3C1PGRCYP3A4NR3C2 | |
| SCHEMBL4555711 | 0.80 | NR3C1 (0.54) | NR3C1PGRCYP3A4NR3C2 | |
| SCHEMBL3752990 | 0.80 | NR3C1 (0.49) | NR3C1PGRCYP3A4NR3C2 | |
| SCHEMBL6669369 | 0.79 | NR3C1 (0.53) | NR3C1PGRCYP3A4NR3C2 | |
| SCHEMBL3748995 | 0.78 | NR3C1 (0.69) | NR3C1PGRCYP3A4NR3C2 | |
| SCHEMBL292965 | 0.78 | NR3C1 (1.00) | NR3C1PGRCYP3A4NR3C2 | |
| SCHEMBL5799170 | 0.77 | NR3C1 (0.50) | NR3C1PGRCYP3A4NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061444-A2 | COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, AMELIORATING, OR PREVENTING ALLERGY | Bausch & Lomb Incorporated (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008033655-A2 | COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, AMELIORATING, OR PREVENTING ALLERGY | BAUSCH & LOMB INCORPORATED (US) | 2008-03-20 | — | — | WO | disclosed |