Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 2/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4556085 | 0.90 | DHPS (0.52) | DHPSNR1H4PPARGPPARAMEN1 | |
| SCHEMBL4556042 | 0.83 | ESR1 (0.49) | NR1H4MEN1KMT2AALDH1A1POLB | |
| SCHEMBL4556084 | 0.82 | DHPS (0.56) | DHPSNR1H4PPARGPPARAMEN1 | |
| SCHEMBL2814444 | 0.82 | KMT2A (0.62) | NR1H4MEN1KMT2AALDH1A1POLB | |
| SCHEMBL4555806 | 0.81 | MEN1 (0.51) | NR1H4PPARGPPARAMEN1KMT2A | |
| SCHEMBL4555727 | 0.79 | FLT3 (0.52) | NR1H4MEN1KMT2ACLK4ALDH1A1 | |
| SCHEMBL4446446 | 0.78 | PIN1 (0.56) | NR1H4PPARGPPARAMEN1KMT2A | |
| SCHEMBL4556269 | 0.77 | PLAU (0.47) | NR1H4MEN1KMT2AALDH1A1POLB | |
| SCHEMBL4556335 | 0.77 | NPC1 (0.58) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL4556079 | 0.77 | AAK1 (0.53) | NR1H4PPARGPPARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | disclosed |