Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 2/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2818006 | 0.89 | MEN1 (0.53) | NR1H4MEN1KMT2APKMROCK2 | |
| SCHEMBL4556085 | 0.86 | DHPS (0.52) | DHPSNR1H4TUBB4ATUBBTUBA3C | |
| SCHEMBL2815122 | 0.84 | KMT2A (0.57) | NR1H4MEN1KMT2APKMROCK2 | |
| SCHEMBL4556043 | 0.84 | ESR1 (0.50) | NR1H4MEN1KMT2APKMROCK2 | |
| SCHEMBL4563838 | 0.83 | NR1H4 (0.45) | NR1H4MEN1KMT2APKMROCK2 | |
| SCHEMBL4556083 | 0.82 | DHPS (0.53) | DHPSNR1H4TUBB4ATUBBTUBA3C | |
| SCHEMBL2814902 | 0.82 | MAPT (0.61) | NR1H4MEN1KMT2APKMROCK2 | |
| SCHEMBL2816819 | 0.81 | MEN1 (0.63) | NR1H4MEN1KMT2APKMROCK2 | |
| SCHEMBL4555807 | 0.80 | KMT2A (0.50) | NR1H4MEN1KMT2APKMALDH1A1 | |
| SCHEMBL4564334 | 0.80 | ROCK2 (0.45) | NR1H4MEN1KMT2APKMROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | disclosed |