Methane

Methane

SCHEMBL455609

C.C.NC(O)=S.NC(O)=S

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.56
ATM Q13315 1/20 0.56
ATR Q13535 1/20 0.56
ALDH1A1 P00352 2/20 0.39
HSD17B10 Q99714 2/20 0.39
PTGS2 P35354 1/20 0.39
HPGD P15428 1/20 0.39
ACHE P22303 1/20 0.36
LDHA P00338 1/20 0.31
LDHB P07195 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL11423626 1.00 TSHR (0.56) TSHRATMATRALDH1A1HSD17B10
Methane SCHEMBL5794637 1.00
Methane SCHEMBL29389420 1.00
Methane SCHEMBL8838996 1.00 TSHR (0.56) TSHRATMATRALDH1A1HSD17B10
Methane SCHEMBL202667 0.94 TSHR (0.50) TSHRATMATRALDH1A1HSD17B10
Methane SCHEMBL10939053 0.94 TSHR (0.50) TSHRATMATRALDH1A1HSD17B10
Methane SCHEMBL1442993 0.94 TSHR (0.50) TSHRATMATRALDH1A1HSD17B10
Methane SCHEMBL1900735 0.94 TSHR (0.50) TSHRATMATRALDH1A1HSD17B10
Methane SCHEMBL8604501 0.94 TSHR (0.50) TSHRATMATRALDH1A1HSD17B10
Methane SCHEMBL11037799 0.94 TSHR (0.50) TSHRATMATRALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4255414-B1 COMPOSITION CONTAINING RANITIDINE HAVING A LOW IRON CONTENT OPELLA HEALTHCARE GROUP SAS (FR) 2025-02-05 EP claimed
CN-119113470-A Heavy metal curing agent for treating arsenic-containing fly ash and application thereof 宝武集团环境资源科技有限公司 2024-12-13 CN claimed
WO-2024046450-A1 METAL PLATING COMPOSITION AND USE METHOD THEREFOR 宁波安集微电子科技有限公司 2024-03-07 WO claimed
WO-2024046447-A1 METAL ELECTROPLATING COMPOSITION FOR ELECTROLYTIC COPPER COATING AND USE METHOD THEREFOR 宁波安集微电子科技有限公司 2024-03-07 WO claimed
US-20240024278-A1 COMPOSITION CONTAINING RANITIDINE HAVING A LOW IRON CONTENT SANOFI CHIMIE (FR) 2024-01-25 US claimed
CN-116887824-A Compositions containing ranitidine with low iron content 欧彼乐医疗集团公司 2023-10-13 CN claimed
EP-4255414-A1 COMPOSITION CONTAINING RANITIDINE HAVING A LOW IRON CONTENT Opella Healthcare Group SAS (FR) 2023-10-11 EP claimed
EP-3976878-B1 METHODS OF MAKING A DEFLECTION MEMBER PROCTER & GAMBLE (US) 2023-07-05 EP claimed
WO-2022117771-A1 COMPOSITION CONTAINING RANITIDINE HAVING A LOW IRON CONTENT OPELLA HEALTHCARE GROUP SAS (FR) 2022-06-09 WO claimed
EP-3299427-B1 ANTIFOULING COATING MATERIAL COMPOSITION, ANTIFOULING COATING FILM, ANTIFOULING BASE, METHOD FOR PRODUCING ANTIFOULING BASE, AND METHOD FOR STORING ANTIFOULING COATING MATERIAL COMPOSITION CHUGOKU MARINE PAINTS (JP) 2020-06-17 EP claimed
EP-3305819-B1 ITACONATE/BUTADIENE COPOLYMER TYPE BIOENGINEERING RUBBER AND PREPARATION METHOD THEREFOR UNIV BEIJING CHEM TECH (CN) 2020-04-22 EP claimed
EP-1742993-B1 RUBBER COMPOSITION AND TIRE COMPRISING SAME MICHELIN & CIE (FR) 2018-07-04 EP claimed
EP-1564255-B1 Photobase generator and curable composition MITSUBISHI GAS CHEMICAL CO (JP) 2007-09-26 EP claimed
WO-1999034926-A1 METHOD FOR RECOVERING AND SEPARATING METALS FROM WASTE STREAMS KREISLER LAWRENCE (US) 1999-07-15 WO claimed
EP-0435554-B1 Rubber compositions and preparation thereof SHINETSU CHEMICAL CO (JP) 1996-03-13 EP claimed
EP-0549006-A2 Ammonium and phosphonium salts and their use as biocides FMC CORPORATION (UK) LIMITED (GB) 1993-06-30 EP claimed
EP-0137331-B1 PREPARATION OF OZONE RESISTANT PRINTING PLATES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-08-26 EP claimed
JP-55094381-A None JP disclosed
US-3976769-A INSECTICIDE AIRWICK INDUSTRIES, INC. (US) 1976-08-24 US disclosed
US-3933715-A N-substituted maleic imide preservative for aqueous dispersions of polymers derived from α, β-ethylenically unsaturated monomers HOECHST AKTIENGESELLSCHAFT (DT) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240024278-A1 COMPOSITION CONTAINING RANITIDINE HAVING A LOW IRON CONTENT TFRC, HAMP, HRH2 TSHR 2722/4885ATM 4882/4885ATR 4605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.