Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555550 | 0.78 | SMN1; SMN2 (0.60) | KMT2AMEN1ALDH1A1PKMNPC1 | |
| SCHEMBL2813712 | 0.77 | KMT2A (0.67) | KMT2AMEN1ALDH1A1PKMNPC1 | |
| SCHEMBL2816819 | 0.77 | MEN1 (0.63) | KMT2AMEN1ALDH1A1PKMNPC1 | |
| SCHEMBL2815071 | 0.77 | MEN1 (0.54) | KMT2AMEN1ALDH1A1PKMNPC1 | |
| SCHEMBL2814955 | 0.76 | ALDH1A1 (0.65) | KMT2AMEN1ALDH1A1PKMNPC1 | |
| SCHEMBL2816590 | 0.75 | LMNA (0.62) | KMT2AMEN1ALDH1A1PKMNPC1 | |
| SCHEMBL4556270 | 0.75 | MEN1 (0.45) | KMT2AMEN1ALDH1A1PKMNPC1 | |
| SCHEMBL2819556 | 0.75 | MEN1 (0.56) | KMT2AMEN1ALDH1A1PKMNPC1 | |
| SCHEMBL2815527 | 0.75 | MEN1 (0.56) | KMT2AMEN1ALDH1A1PKMNPC1 | |
| SCHEMBL2820235 | 0.75 | TSHR (0.59) | KMT2AMEN1ALDH1A1PKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | disclosed |