SCHEMBL4556356

SCHEMBL4556356

C=CC(O)OC(=O)c1ccccc1C(=O)OC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.49
TSHR P16473 2/20 0.49
ALDH1A1 P00352 2/20 0.47
CFTR P13569 1/20 0.47
HSD17B10 Q99714 1/20 0.47
KDM4E B2RXH2 2/20 0.46
POLB P06746 1/20 0.46
ATM Q13315 1/20 0.46
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA5A P35218 1/20 0.42
CA9 Q16790 1/20 0.42
MAPT P10636 1/20 0.42
ALOX15 P16050 1/20 0.42
KMT2A Q03164 1/20 0.42
CYP3A4 P08684 1/20 0.42
SLC6A3 Q01959 3/20 0.41
MYC P01106 1/20 0.41
HPGD P15428 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6257193 0.91 CYP3A4 (0.48) LMNATSHRALDH1A1HSD17B10KDM4E
SCHEMBL6257197 0.85 ALDH1A1 (0.48) ALDH1A1HSD17B10KDM4EPOLBCA1
SCHEMBL10540667 0.81 LMNA (0.50) LMNATSHRALDH1A1HSD17B10KDM4E
Dimethyl Phthalate SCHEMBL28146247 0.80 TSHR (0.61) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL9720647 0.80 CYP3A4 (0.73) LMNATSHRALDH1A1HSD17B10KDM4E
Dimethyl Phthalate SCHEMBL28238741 0.78 TSHR (0.59) LMNATSHRALDH1A1CFTRHSD17B10
Dimethyl Phthalate SCHEMBL29669976 0.78 TSHR (0.74) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL16606463 0.78 KMT2A (0.48) ALDH1A1KDM4EPOLBATMKMT2A
Dimethyl Phthalate SCHEMBL29500970 0.78 TSHR (0.74) LMNATSHRALDH1A1CFTRHSD17B10
Dimethyl Phthalate SCHEMBL790124 0.78 TSHR (0.74) LMNATSHRALDH1A1CFTRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4294862-B2 2009-07-15 JP claimed
EP-1117736-B2 MODIFIED STARCH FILM COMPOSITIONS WARNER LAMBERT CO (US) 2008-08-13 EP claimed
JP-4065691-B2 2008-03-26 JP claimed
EP-1062274-B1 POLYVINYL ALCOHOL COMPOSITIONS WARNER LAMBERT CO (US) 2007-11-14 EP claimed
EP-1204699-B1 PULLULAN FILM COMPOSITIONS WARNER LAMBERT CO (US) 2005-06-08 EP claimed
US-6887307-B1 Pullulan film compositions WARNER-LAMBERT COMPANY, LLC (US) 2005-05-03 US claimed
EP-1117736-B1 MODIFIED STARCH FILM COMPOSITIONS WARNER LAMBERT CO (US) 2004-07-14 EP claimed
US-20040105835-A1 hydroxpropylated starch (HPS) or hydroxylethylated starch (HES) for the use in pharmaceutical, veterinary, food, cosmetic or other products like films for wrapping food, aspics or jellies, for predosed formulations like soft or hard capsules SCOTT ROBERT A (BE) 2004-06-03 US claimed
US-20030211146-A1 Dipping, molding capsules from starches SCOTT ROBERT A (BE) 2003-11-13 US claimed
JP-2003521551-A 2003-07-15 JP claimed
EP-1117736-A1 MODIFIED STARCH FILM COMPOSITIONS WARNER-LAMBERT COMPANY (US) 2001-07-25 EP claimed
WO-2001007507-A1 PULLULAN FILM COMPOSITIONS WARNER-LAMBERT COMPANY (US) 2001-02-01 WO claimed
EP-1072633-A1 Pullulan film compositions WARNER-LAMBERT COMPANY (US) 2001-01-31 EP claimed
EP-1062274-A1 POLYVINYL ALCOHOL COMPOSITIONS WARNER-LAMBERT COMPANY (US) 2000-12-27 EP claimed
EP-1042405-A1 GELATINE COMPOSITIONS WARNER-LAMBERT COMPANY (US) 2000-10-11 EP claimed
WO-2000018835-A1 MODIFIED STARCH FILM COMPOSITIONS WARNER-LAMBERT COMPANY (US) 2000-04-06 WO claimed
EP-0946637-A1 POLYMER FILM COMPOSITIONS FOR CAPSULES WARNER-LAMBERT COMPANY (US) 1999-10-06 EP claimed
WO-1999046329-A1 POLYVINYL ALCOHOL COMPOSITIONS WARNER-LAMBERT COMPANY (US) 1999-09-16 WO claimed
WO-1999033924-A1 GELATINE COMPOSITIONS WARNER-LAMBERT COMPANY (US) 1999-07-08 WO claimed
WO-1998027151-A1 POLYMER FILM COMPOSITIONS FOR CAPSULES WARNER-LAMBERT COMPANY (US) 1998-06-25 WO claimed