Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4308746 | 0.87 | NAMPT (0.41) | MEN1KMT2ATSHRF7EPHX2 | |
| Hydrochloric Acid SCHEMBL4310570 | 0.86 | NAMPT (0.40) | MEN1KMT2ATSHRF7EPHX2 | |
| SCHEMBL4556460 | 0.84 | VNN1 (0.38) | MEN1KMT2AAURKARPS6KB1 | |
| SCHEMBL4564571 | 0.81 | JAK3 (0.41) | MEN1KMT2AF7RAB9AS1PR3 | |
| SCHEMBL4310295 | 0.74 | CYP2C9 (0.46) | MEN1KMT2ARAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL4309422 | 0.73 | NAMPT (0.43) | EPHX2HDAC1 | |
| SCHEMBL4305726 | 0.71 | NAMPT (0.45) | MEN1KMT2AHDAC1 | |
| SCHEMBL4311618 | 0.70 | EPHX2 (0.46) | MEN1KMT2ACYP2C19EPHX2HDAC1 | |
| Hydrochloric Acid SCHEMBL4303528 | 0.70 | NAMPT (0.44) | MEN1KMT2AHDAC1 | |
| SCHEMBL4309387 | 0.70 | NAMPT (0.44) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |