Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 7/20 | 0.41 |
| ▸ | JAK2 | O60674 | 4/20 | 0.41 |
| ▸ | JAK1 | P23458 | 4/20 | 0.41 |
| ▸ | TYK2 | P29597 | 4/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4308746 | 0.82 | NAMPT (0.41) | NAMPTMEN1KMT2AF7 | |
| SCHEMBL4556654 | 0.81 | MEN1 (0.40) | RAB9AMEN1KMT2AS1PR3TRPV1 | |
| Hydrochloric Acid SCHEMBL4310570 | 0.81 | NAMPT (0.40) | NAMPTMEN1KMT2AF7 | |
| SCHEMBL4303439 | 0.71 | NAMPT (0.53) | NAMPTMEN1KMT2A | |
| SCHEMBL4309422 | 0.70 | NAMPT (0.43) | NAMPT | |
| SCHEMBL1434152 | 0.70 | KLKB1 (0.41) | F7 | |
| SCHEMBL4318995 | 0.70 | NAMPT (0.49) | NAMPT | |
| SCHEMBL4310295 | 0.69 | CYP2C9 (0.46) | RAB9ANAMPTCYP2C9MEN1KMT2A | |
| SCHEMBL4564569 | 0.69 | JAK3 (0.39) | JAK3JAK2JAK1TYK2IRAK4 | |
| Hydrochloric Acid SCHEMBL1907358 | 0.68 | METAP2 (0.41) | JAK3JAK2JAK1TYK2IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |