Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15931886 | 0.84 | HDAC6 (0.59) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL21498359 | 0.80 | HDAC3 (0.54) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL15928822 | 0.80 | HDAC6 (0.54) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL5809506 | 0.79 | RAB9A (0.48) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL5809509 | 0.79 | RAB9A (0.48) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL2428473 | 0.76 | HDAC3 (1.00) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL596141 | 0.76 | HDAC3 (0.63) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| Anetholtrithion SCHEMBL10481903 | 0.75 | MEN1 (0.81) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| Anetholtrithion SCHEMBL9846788 | 0.75 | MEN1 (0.81) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL15951657 | 0.73 | MEN1 (0.63) | HDAC1HDAC6HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037556-A1 | NEW AGENTS FOR THE TREATMENT OF THE LOW URINARY TRACT DYSFUNCTIONS | CTG PHARMA S.R.L. (IT) | 2009-03-26 | — | — | WO | disclosed |
| EP-1980559-A1 | Cardiovascular agents | CTG Pharma S.r.l. (IT) | 2008-10-15 | — | — | EP | disclosed |